Personal profile
Personal profile
Emmanuel Beaurepaire is a specialist in multiphoton microscopy of biological tissues at the Institut Polytechnique de Paris. He works at the Optics and Biosciences Laboratory at École Polytechnique (IP Paris), where he has been appointed research director by the CNRS.
*LOB: a joint research unit of the CNRS, École Polytechnique, Institut Polytechnique de Paris, and Inserm
Research interests
• Advanced microscopies & tissue physiology
→ Multiphoton microscopy of tissues: Large-volume multicolor microscopy • In-depth 3-photon/THG imaging • 2P-light-sheet • Imaging brain development
• Morphoscope imaging facility (Equipex 2013-2023)
• ERC-SyG HOPE project (2021-2027)
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Collaborations and top research areas from the last five years
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Erratum: Third-harmonic generation microscopy with focus-engineered beams: a numerical study (Opt. Express (2008) 16:19 (14703–14715) DOI: 10.1364/OE.16.014703)
Olivier, N. & Beaurepaire, E., 8 Sept 2025, In: Optics Express. 33, 18, p. 37507-37508 2 p.Research output: Contribution to journal › Comment/debate
Open Access -
Label-free nonlinear microscopy probes cellular metabolism and myelin dynamics in live tissue
Asadipour, B., Morizet, J., Ronzano, R., Zhang, X., Aigrot, M. S., Mahou, P., Solinas, X., Phan, M. S., Chessel, A., Stankoff, B., Desmazieres, A., Beaurepaire, E. & Stringari, C., 1 Dec 2025, In: Communications Biology. 8, 1, 1811.Research output: Contribution to journal › Article › peer-review
Open Access -
Mapping metabolism and myelin dynamics in live brain tissue by label-free multimodal non-linear microscopy
Asadipour, B., Morizet, J., Ronzano, R., Zhang, X., Chessel, A., Mahou, P., Solinas, X., Aigrot, M. S., Desmazieres, A., Stankoff, B., Beaurepaire, E. & Stringari, C., 1 Jan 2025.Research output: Contribution to conference › Paper › peer-review
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Modelling and predicting second harmonic generation from protein molecular structure
Asadipour, B., Beaurepaire, E., Zhang, X., Chessel, A., Mahou, P., Supatto, W., Schanne-Klein, M. C. & Stringari, C., 18 Dec 2025, Advances in Microscopic Imaging V. Ben-Yakar, A. & Stringari, C. (eds.). SPIE, 139370V. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 13937).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review
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Modelling and predicting Second Harmonic Generation from protein molecular structure
Asadipour, B., Beaurepaire, E., Zhang, X., Chessel, A., Mahou, P., Supatto, W., Schanne-Klein, M. C. & Stringari, C., 1 Jan 2025, European Conference on Biomedical Optics, ECBO 2025. Optical Society of America, (European Conference on Biomedical Optics, ECBO 2025).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review
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Multiscale characterization of myelin distribution with polarized THG microscopy
Morizet, J., Olivier, N., Aigrot, M. S., Mahou, P., Martin, E., Desmazieres, A., Stankoff, B., Stringari, C. & Beaurepaire, E., 20 Jul 2025, In: Optica. 12, 7, p. 1122-1138 17 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Modeling and Predicting Second-Harmonic Generation from Protein Molecular Structure
Asadipour, B., Beaurepaire, E., Zhang, X., Chessel, A., Mahou, P., Supatto, W., Schanne-Klein, M. C. & Stringari, C., 1 Jan 2024, In: Physical Review X. 14, 1, 011038.Research output: Contribution to journal › Article › peer-review
Open Access -
Multiplexed Orthogonal Polarizations Harmonic Imaging for Probing Dynamic Biological Processes
Gleeson, M., Escot, S., Solinas, X., Asadipour, B., Supatto, W., Mahou, P., Stringari, C. & Beaurepaire, E., 21 Aug 2024, In: ACS Photonics. 11, 8, p. 3259-3266 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Non-random spatial organization of telomeres varies during the cell cycle and requires LAP2 and BAF
Keller, D., Stinus, S., Umlauf, D., Gourbeyre, E., Biot, E., Olivier, N., Mahou, P., Beaurepaire, E., Andrey, P. & Crabbe, L., 19 Apr 2024, In: iScience. 27, 4, 109343.Research output: Contribution to journal › Article › peer-review
Open Access -
Understanding the cell fate and behavior of progenitors at the origin of the mouse cardiac mitral valve
Farhat, B., Bordeu, I., Jagla, B., Ibrahim, S., Stefanovic, S., Blanc, H., Loulier, K., Simons, B. D., Beaurepaire, E., Livet, J. & Pucéat, M., 5 Feb 2024, In: Developmental Cell. 59, 3, p. 339-350.e4Research output: Contribution to journal › Article › peer-review
Open Access