Personal profile
Personal profile
Hannu Myllykallio is responsible for the research theme "Molecular mechanisms of microbial adaptation" at LOB* at the École polytechnique. He earned his PhD from the University of Pennsylvania, Philadelphia, studying biological energy conversion in photosynthetic bacteria, followed by postdoctoral research on microbial DNA replication and repair in the Paris region. He uses a wide range of computational and experimental methods to understand the molecular mechanisms underlying antimicrobial resistance and genome stability in prokaryotic cells.
*LOB: Laboratory of optics and biosciences, a joint research unit CNRS, Ecole polytechnique - Institut Polytechnique de Paris, Inserm
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
-
Additive CHARMM Force Field for Pterins and Folates
Balduzzi, E., Yin, W., Lambry, J. C., Myllykallio, H. & Aleksandrov, A., 5 Jan 2025, In: Journal of Computational Chemistry. 46, 1, e27548.Research output: Contribution to journal › Article › peer-review
Open Access -
Archaeal DNA Repair
L’hermitte-Stead, C., Bayard, A., Aleksandrov, A., Lestini, R. & Myllykallio, H., 1 Jan 2025, Biology of Archaea 2: Molecular Biology of Archaea, From Genome Maintenance to the Regulation of Gene Expression. wiley, p. 25-44 20 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
-
Editorial: The metabolic pathways of archaea
Myllykallio, H., Qin, W. & Berg, I. A., 1 Jan 2025, In: Frontiers in Microbiology. 16, 1648560.Research output: Contribution to journal › Editorial
Open Access -
Genome-wide ribonucleotide detection in Archaea
Moalic, Y., Reveil, M., Kundnani, D. L., Balachander, S., Yang, T., Gombolay, A., Ranjbarian, F., Brizard, R., Durand, P., Myllykallio, H., Jebbar, M., Hofer, A., Storici, F. & Henneke, G., 26 Nov 2025, In: Nucleic Acids Research. 53, 21, gkaf1231.Research output: Contribution to journal › Article › peer-review
Open Access -
Understanding the key challenges in tuberculosis drug discovery: what does the future hold?
Zein-Eddine, R., Ramuz, M., Refrégier, G., Lutzeyer, J. F., Aleksandrov, A. & Myllykallio, H., 1 Jan 2025, In: Expert Opinion on Drug Discovery. 20, 9, p. 1115-1130 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Correction of non-random mutational biases along a linear bacterial chromosome by the mismatch repair endonuclease NucS
Dagva, O., Thibessard, A., Lorenzi, J. N., Labat, V., Piotrowski, E., Rouhier, N., Myllykallio, H., Leblond, P. & Bertrand, C., 22 May 2024, In: Nucleic Acids Research. 52, 9, p. 5033-5047 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Bacterial origins of thymidylate metabolism in Asgard archaea and Eukarya
Filée, J., Becker, H. F., Mellottee, L., Eddine, R. Z., Li, Z., Yin, W., Lambry, J. C., Liebl, U. & Myllykallio, H., 1 Dec 2023, In: Nature Communications. 14, 1, 838.Research output: Contribution to journal › Article › peer-review
Open Access -
BrdU Incorporation and Labeling of Nascent DNA to Investigate Archaeal Replication Using Super-Resolution Imaging
Lestini, R., Collien, Y., Olivier, D., Olivier, N. & Myllykallio, H., 1 Jan 2022, Methods in Molecular Biology. Humana Press Inc., p. 419-434 16 p. (Methods in Molecular Biology; vol. 2522).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
Open Access -
Synthesis and Structure–Activity Relationship Studies of Pyrido [1,2-e]Purine-2,4(1H,3H)-Dione Derivatives Targeting Flavin-Dependent Thymidylate Synthase in Mycobacterium tuberculosis
Biteau, N. G., Roy, V., Nicolas, C., Becker, H. F., Lambry, J. C., Myllykallio, H. & Agrofoglio, L. A., 1 Oct 2022, In: Molecules. 27, 19, 6216.Research output: Contribution to journal › Article › peer-review
Open Access -
Cyclodipeptide Synthases of the NYH Subfamily Recognize tRNA Using an α-Helix Enriched with Positive Residues
Croitoru, A., Babin, M., Myllykallio, H., Gondry, M. & Aleksandrov, A., 12 Jan 2021, In: Biochemistry. 60, 1, p. 64-76 13 p.Research output: Contribution to journal › Article › peer-review
Open Access