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Dive into the research topics where Lionel Guittat is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Archaeal G-quadruplexes: a novel model for understanding unusual DNA/RNA structures across the tree of life
Aktary, Z., Sorg, K., Cucchiarini, A., Vesco, G., Noury, D., Zhang, R., Jourdain, T., Verga, D., Mahou, P., Olivier, N., Bohálová, N., Porubiaková, O., Brázda, V., Bouvier, M., Kwapisz, M., Clouet-D’Orval, B., Allers, T., Lestini, R., Mergny, J. L. & Guittat, L., 27 Feb 2026, In: Nucleic Acids Research. 54, 4, gkag067.Research output: Contribution to journal › Article › peer-review
Open Access -
Lysosomal damage due to cholesterol accumulation triggers immunogenic cell death
Alvarez-Valadez, K., Sauvat, A., Diharce, J., Leduc, M., Stoll, G., Guittat, L., Lambertucci, F., Paillet, J., Motiño, O., Ferret, L., Muller, A., Forveille, S., Maiuri, M. C., Kepp, O., de Brevern, A. G., Wodrich, H., Pol, J. G., Kroemer, G. & Djavaheri-Mergny, M., 1 Jan 2025, In: Autophagy. 21, 5, p. 934-956 23 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Lysosomal membrane permeabilization enhances the anticancer effects of POLR1 (RNA polymerase I) transcription inhibitors
Ferret, L., Pol, J. G., Sauvat, A., Stoll, G., Alvarez-Valadez, K., Muller, A., Le Naour, J., Peyre, F., Anagnostopoulos, G., Martins, I., Maiuri, M. C., Wodrich, H., Guittat, L., Mergny, J. L., Kroemer, G. & Djavaheri-Mergny, M., 1 Jan 2025, In: Autophagy. 21, 10, p. 2246-2265 20 p.Research output: Contribution to journal › Article › peer-review
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Ultra-Specific G-Quadruplex-Colistin Interaction for Efficient Transcriptome-Wide G4 Mapping
Wei, S., Zhang, X., Feng, Y., Tao, S., Qiu, D., Yan, X., Li, G., Guittat, L., Zhang, W., Monchaud, D., Mergny, J. L., Ju, H. & Zhou, J., 19 Mar 2025, In: Journal of the American Chemical Society. 147, 11, p. 9962-9971 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
G-quadruplex ligands as potent regulators of lysosomes
Ferret, L., Alvarez-Valadez, K., Rivière, J., Muller, A., Bohálová, N., Yu, L., Guittat, L., Brázda, V., Kroemer, G., Mergny, J. L. & Djavaheri-Mergny, M., 1 Jan 2023, In: Autophagy. 19, 7, p. 1901-1915 15 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
G-quadruplexes in helminth parasites
Cantara, A., Luo, Y., Dobrovolná, M., Bohalova, N., Fojta, M., Verga, D., Guittat, L., Cucchiarini, A., Savrimoutou, S., Häberli, C. D. S., Guillon, J., Keiser, J., Brázda, V. & Mergny, J. L., 21 Mar 2022, In: Nucleic Acids Research. 50, 5, p. 2719-2735 17 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Are telomeres and telomerase still relevant targets in oncology?
Mergny, J. L., Guittat, L. & Ségal-Bendirdjian, É., 1 Jan 2021, In: Bulletin du Cancer. 108, 1, p. 30-38 9 p.Research output: Contribution to journal › Letter › peer-review
Open Access -
Regulatory interplay between Vav1, Syk and β-catenin occurs in lung cancer cells
Boudria, R., Laurienté, V., Oudar, A., Harouna-Rachidi, S., Dondi, E., Le Roy, C., Gardano, L., Varin-Blank, N. & Guittat, L., 1 Oct 2021, In: Cellular Signalling. 86, 110079.Research output: Contribution to journal › Article › peer-review
Open Access -
SARS-CoV-2 Nsp3 unique domain SUD interacts with guanine quadruplexes and G4-ligands inhibit this interaction
Lavigne, M., Helynck, O., Rigolet, P., Boudria-Souilah, R., Nowakowski, M., Baron, B., Brülé, S., Hoos, S., Raynal, B., Guittat, L., Beauvineau, C., Petres, S., Granzhan, A., Guillon, J., Pratviel, G., Teulade-Fichou, M. P., England, P., Mergny, J. L. & Munier-Lehmann, H., 21 Jul 2021, In: Nucleic Acids Research. 49, 13, p. 7695-7712 18 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Protein kinase D-dependent CXCR4 down-regulation upon BCR triggering is linked to lymphadenopathy in chronic lymphocytic leukaemia
Saint-Georges, S., Quettier, M., Bouyaba, M., Le Coquil, S., Laurienté, V., Guittat, L., Lévy, V., Ajchenbaum-Cymbalista, F., Varin-Blank, N., Le Roy, C. & Ledoux, D., 5 Jul 2016, In: Oncotarget. 7, 27, p. 41031-41046 16 p.Research output: Contribution to journal › Article › peer-review
Open Access