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Dive into the research topics where Pierre-Antoine Defossez is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Déméthyler l’ADN contre le cancer - Vers de nouvelles stratégies épigénétiques sans dommage à l’ADN
Translated title of the contribution :Demethylating DNA against cancer: towards new epigenetic therapeutic strategies without DNA damage Research output: Contribution to journal › Article › peer-review
Open Access -
DNA methylation protects cancer cells against senescence
Chen, X., Yamaguchi, K., Rodgers, B., Goehrig, D., Vindrieux, D., Lahaye, X., Nolot, M., Ferry, L., Lanciano, S., Martin, N., Dubus, P., Miura, F., Ito, T., Cristofari, G., Manel, N., Kanemaki, M. T., Bernard, D. & Defossez, P. A., 1 Dec 2025, In: Nature Communications. 16, 1, 5901.Research output: Contribution to journal › Article › peer-review
Open Access -
Editorial Expression of Concern: Identification of oncogenic microRNA-17-92/ZBTB4/specificity protein axis in breast cancer(Oncogene, 10.1038/onc.2011.296)
Kim, K., Chadalapaka, G., Lee, S. O., Yamada, D., Sastre-Garau, X., Defossez, P. A., Park, Y. Y., Lee, J. S. & Safe, S., 28 Apr 2025, In: Oncogene. 44, 15, p. 1064 1 p.Research output: Contribution to journal › Comment/debate
Open Access -
A novel bioinformatic approach reveals cooperation between Cancer/Testis genes in basal-like breast tumors
Laisné, M., Rodgers, B., Benlamara, S., Wicinski, J., Nicolas, A., Djerroudi, L., Gupta, N., Ferry, L., Kirsh, O., Daher, D., Philippe, C., Okada, Y., Charafe-Jauffret, E., Cristofari, G., Meseure, D., Vincent-Salomon, A., Ginestier, C. & Defossez, P. A., 2 May 2024, In: Oncogene. 43, 18, p. 1369-1385 17 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Chromatin and transcription in Nucleic Acids Research: the first 50 years
Defossez, P. A., 11 Dec 2024, In: Nucleic Acids Research. 52, 22, p. 13485-13489 5 p.Research output: Contribution to journal › Editorial
Open Access -
Comprendre la totipotence embryonnaire à partir des cellules 2C-like
Translated title of the contribution :Using 2C-like cells to understand embryonic totipotency Research output: Contribution to journal › Review article › peer-review
Open Access -
Locus-level L1 DNA methylation profiling reveals the epigenetic and transcriptional interplay between L1s and their integration sites
Lanciano, S., Philippe, C., Sarkar, A., Pratella, D., Domrane, C., Doucet, A. J., van Essen, D., Saccani, S., Ferry, L., Defossez, P. A. & Cristofari, G., 14 Feb 2024, In: Cell Genomics. 4, 2, 100498.Research output: Contribution to journal › Article › peer-review
Open Access -
Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells
Yamaguchi, K., Chen, X., Rodgers, B., Miura, F., Bashtrykov, P., Bonhomme, F., Salinas-Luypaert, C., Haxholli, D., Gutekunst, N., Aygenli, B. Ö., Ferry, L., Kirsh, O., Laisné, M., Scelfo, A., Ugur, E., Arimondo, P. B., Leonhardt, H., Kanemaki, M. T., Bartke, T. & Fachinetti, D. & 3 others, , 1 Dec 2024, In: Nature Communications. 15, 1, 2960.Research output: Contribution to journal › Article › peer-review
Open Access -
A genetic screen identifies BEND3 as a regulator of bivalent gene expression and global DNA methylation
Yakhou, L., Azogui, A., Gupta, N., Richard Albert, J., Miura, F., Ferry, L., Yamaguchi, K., Battault, S., Therizols, P., Bonhomme, F., Bethuel, E., Sarkar, A., Greenberg, M. V. C., Arimondo, P. B., Cristofari, G., Kirsh, O., Ito, T. & Defossez, P. A., 27 Oct 2023, In: Nucleic Acids Research. 51, 19, p. 10292-10308 17 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A genome-wide screen reveals new regulators of the 2-cell-like cell state
Gupta, N., Yakhou, L., Albert, J. R., Azogui, A., Ferry, L., Kirsh, O., Miura, F., Battault, S., Yamaguchi, K., Laisné, M., Domrane, C., Bonhomme, F., Sarkar, A., Delagrange, M., Ducos, B., Cristofari, G., Ito, T., Greenberg, M. V. C. & Defossez, P. A., 1 Aug 2023, In: Nature Structural and Molecular Biology. 30, 8, p. 1105-1118 14 p.Research output: Contribution to journal › Article › peer-review