A domino ring-closing metathesis as a key-step in the synthesis of chiral lactones from D-mannitol

Bastien Nay; Nicolas Gaboriaud-Kolar; Bernard Bodo

doi:10.1016/j.tetlet.2005.03.189

A domino ring-closing metathesis as a key-step in the synthesis of chiral lactones from D-mannitol

Bastien Nay
, Nicolas Gaboriaud-Kolar
, Bernard Bodo

CNRS/Museum National d'Histoire Naturelle/IRD/UPMC

Research output: Contribution to journal › Article › peer-review

Abstract

Chiral lactones were synthesized in six steps from D-mannitol. The key-step was a domino ring-closing metathesis reaction leading to the symmetric cleavage of a D-mannitol triene derivative and to the formation of two molecules of the desired lactone.

Original language	English
Pages (from-to)	3867-3870
Number of pages	4
Journal	Tetrahedron Letters
Volume	46
Issue number	22
DOIs	https://doi.org/10.1016/j.tetlet.2005.03.189
Publication status	Published - 30 May 2005
Externally published	Yes

Keywords

Chiral pool
Domino metathesis
Lactones

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10.1016/j.tetlet.2005.03.189

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title = "A domino ring-closing metathesis as a key-step in the synthesis of chiral lactones from D-mannitol",

abstract = "Chiral lactones were synthesized in six steps from D-mannitol. The key-step was a domino ring-closing metathesis reaction leading to the symmetric cleavage of a D-mannitol triene derivative and to the formation of two molecules of the desired lactone.",

keywords = "Chiral pool, Domino metathesis, Lactones",

author = "Bastien Nay and Nicolas Gaboriaud-Kolar and Bernard Bodo",

year = "2005",

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language = "English",

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T1 - A domino ring-closing metathesis as a key-step in the synthesis of chiral lactones from D-mannitol

AU - Nay, Bastien

AU - Gaboriaud-Kolar, Nicolas

AU - Bodo, Bernard

PY - 2005/5/30

Y1 - 2005/5/30

N2 - Chiral lactones were synthesized in six steps from D-mannitol. The key-step was a domino ring-closing metathesis reaction leading to the symmetric cleavage of a D-mannitol triene derivative and to the formation of two molecules of the desired lactone.

AB - Chiral lactones were synthesized in six steps from D-mannitol. The key-step was a domino ring-closing metathesis reaction leading to the symmetric cleavage of a D-mannitol triene derivative and to the formation of two molecules of the desired lactone.

KW - Chiral pool

KW - Domino metathesis

KW - Lactones

UR - https://www.scopus.com/pages/publications/18144418558

U2 - 10.1016/j.tetlet.2005.03.189

DO - 10.1016/j.tetlet.2005.03.189

M3 - Article

AN - SCOPUS:18144418558

SN - 0040-4039

VL - 46

SP - 3867

EP - 3870

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 22

ER -

A domino ring-closing metathesis as a key-step in the synthesis of chiral lactones from D-mannitol

Abstract

Keywords

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