A flexible route to 4-substituted β-lactams

Béatrice Quiclet-Sire; Samir Z. Zard

doi:10.3987/COM-10-S(E)39

A flexible route to 4-substituted β-lactams

Béatrice Quiclet-Sire
, Samir Z. Zard

Laboratoire de Synthèse Organique

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

A variety of 4-substituted β-lactams can be readily prepared by the radical addition-transfer of 4-S-xanthyl-azetidinones to unactivated olefins. For this radical chain process to operate efficiently it is necessary to place an acyl group on the nitrogen of the azetidinone ring.

Original language	English
Pages (from-to)	263-271
Number of pages	9
Journal	Heterocycles
Volume	82
Issue number	1
DOIs	https://doi.org/10.3987/COM-10-S(E)39
Publication status	Published - 1 Dec 2010
Externally published	Yes

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10.3987/COM-10-S(E)39

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title = "A flexible route to 4-substituted β-lactams",

abstract = "A variety of 4-substituted β-lactams can be readily prepared by the radical addition-transfer of 4-S-xanthyl-azetidinones to unactivated olefins. For this radical chain process to operate efficiently it is necessary to place an acyl group on the nitrogen of the azetidinone ring.",

author = "B{\'e}atrice Quiclet-Sire and Zard, \{Samir Z.\}",

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N2 - A variety of 4-substituted β-lactams can be readily prepared by the radical addition-transfer of 4-S-xanthyl-azetidinones to unactivated olefins. For this radical chain process to operate efficiently it is necessary to place an acyl group on the nitrogen of the azetidinone ring.

AB - A variety of 4-substituted β-lactams can be readily prepared by the radical addition-transfer of 4-S-xanthyl-azetidinones to unactivated olefins. For this radical chain process to operate efficiently it is necessary to place an acyl group on the nitrogen of the azetidinone ring.

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DO - 10.3987/COM-10-S(E)39

M3 - Article

AN - SCOPUS:79751510345

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VL - 82

SP - 263

EP - 271

JO - Heterocycles

JF - Heterocycles

IS - 1

ER -

A flexible route to 4-substituted β-lactams

Abstract

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