Abstract
A variety of α-branched alkynes can be easily assembled by a Knoevenagel type condensation of 4-unsubstituted isoxazolin-5-ones with aldehydes or ketones, followed by conjugate addition of an organometallic reagent and nitrosative cleavage of the heterocyclic ring.
| Original language | English |
|---|---|
| Pages (from-to) | 1257-1260 |
| Number of pages | 4 |
| Journal | Synlett |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - 1 Jan 2002 |
| Externally published | Yes |
Keywords
- Alkynes
- Conjugate addition
- Isoxazolin-5-ones
- Knoevenagel condensation
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