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A new synthesis of 3-aryl substituted oxindoles

  • Centre national de la recherche scientifique
  • Laboratoire de Synthèse Organique

Research output: Contribution to journalArticlepeer-review

Abstract

A variety of 3-aryl substituted oxindoles can be rapidly constructed by treatment of a suitable 2,2-dimethoxy arylacetanilide, with titanium tetrachloride or boron trifluoride etherate; the synthesis of the precursors hinges on a powerful reaction between arylacetic acids and thionyl chloride.

Original languageEnglish
Pages (from-to)4889-4898
Number of pages10
JournalTetrahedron
Volume54
Issue number19
DOIs
Publication statusPublished - 1 May 1998

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