A practical variation on the Paal-Knorr pyrrole synthesis

Béatrice Quiclet-Sire; Leticia Quintero; Graciela Sanchez-Jimenez; Samir Z. Zard

A practical variation on the Paal-Knorr pyrrole synthesis

Béatrice Quiclet-Sire
, Leticia Quintero
, Graciela Sanchez-Jimenez
, Samir Z. Zard

Laboratoire de Synthèse Organique
C. I. de la F. de C. Q. U. A. de P.

Research output: Contribution to journal › Article › peer-review

68 Citations (Scopus)

Abstract

The radical addition of α-xanthyl ketones to vinyl pivalate gives adducts that are synthetic equivalents of 1,4-ketoaldehydes; treatment with ammonia or primary amines leads to the corresponding pyrroles in high yield.

Original language	English
Pages (from-to)	75-78
Number of pages	4
Journal	Synlett
Issue number	1
Publication status	Published - 1 Jan 2003
Externally published	Yes

Keywords

Furans
Paal-Knorr reaction
Pyrroles
Radical additions
Xanthates

Cite this

@article{317852f633474ffaa099d1cb3c3ffecf,

title = "A practical variation on the Paal-Knorr pyrrole synthesis",

abstract = "The radical addition of α-xanthyl ketones to vinyl pivalate gives adducts that are synthetic equivalents of 1,4-ketoaldehydes; treatment with ammonia or primary amines leads to the corresponding pyrroles in high yield.",

keywords = "Furans, Paal-Knorr reaction, Pyrroles, Radical additions, Xanthates",

author = "B{\'e}atrice Quiclet-Sire and Leticia Quintero and Graciela Sanchez-Jimenez and Zard, \{Samir Z.\}",

year = "2003",

month = jan,

day = "1",

language = "English",

pages = "75--78",

journal = "Synlett",

issn = "0936-5214",

publisher = "Georg Thieme Verlag",

number = "1",

}

TY - JOUR

T1 - A practical variation on the Paal-Knorr pyrrole synthesis

AU - Quiclet-Sire, Béatrice

AU - Quintero, Leticia

AU - Sanchez-Jimenez, Graciela

AU - Zard, Samir Z.

PY - 2003/1/1

Y1 - 2003/1/1

N2 - The radical addition of α-xanthyl ketones to vinyl pivalate gives adducts that are synthetic equivalents of 1,4-ketoaldehydes; treatment with ammonia or primary amines leads to the corresponding pyrroles in high yield.

AB - The radical addition of α-xanthyl ketones to vinyl pivalate gives adducts that are synthetic equivalents of 1,4-ketoaldehydes; treatment with ammonia or primary amines leads to the corresponding pyrroles in high yield.

KW - Furans

KW - Paal-Knorr reaction

KW - Pyrroles

KW - Radical additions

KW - Xanthates

M3 - Article

AN - SCOPUS:0037240917

SN - 0936-5214

SP - 75

EP - 78

JO - Synlett

JF - Synlett

IS - 1

ER -

A practical variation on the Paal-Knorr pyrrole synthesis

Abstract

Keywords

Fingerprint

Cite this