A proportional hazards regression model with change-points in the baseline function

Research output: Contribution to journalArticlepeer-review

Abstract

In this article, we consider a new regression model for counting processes under a proportional hazards assumption. This model is motivated by the need of understanding the evolution of the booking process of a railway company. The main novelty of the approach consists in assuming that the baseline hazard function is piecewise constant, with unknown times of jump (these times of jump are estimated from the data as model parameters). Hence, the parameters of the model can be separated into two different types: parameters that measure the influence of the covariates, and parameters from a multiple change-point model for the baseline. Cox's semiparametric regression can be seen as a limit case of our model. We develop an iterative procedure to estimate the different parameters, and a test procedure that allows to perform change-point detection in the baseline. Our technique is supported by simulation studies and a real data analysis, which show that our model can be a reasonable alternative to Cox's regression model, particularly in the presence of tied event times.

Original languageEnglish
Pages (from-to)59-78
Number of pages20
JournalLifetime Data Analysis
Volume19
Issue number1
DOIs
Publication statusPublished - 1 Dec 2012
Externally publishedYes

Keywords

  • Change-point detection
  • Dynamic programming
  • Iterative procedures
  • Proportional hazards regression
  • Recurrent events
  • Revenue-management
  • Survival analysis

Fingerprint

Dive into the research topics of 'A proportional hazards regression model with change-points in the baseline function'. Together they form a unique fingerprint.

Cite this