A Reliable Method to Predict Parkinson's Disease Stage and Progression based on Handwriting and Re-sampling Approaches

Catherine Taleb, Maha Khachab, Chafic Mokbel, Laurence Likforman-Sulem

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

A reliable system depending on algorithms that assist in the decision-making process to diagnose Parkinson's disease (PD) at an early stage and to predict the Hoehn Yahr (HY) stage and the unified Parkinson's disease rating scale (UPDRS) score is developed. In a previous work [3], we used features extracted from Arabic handwriting for diagnosing PD as binary decision. In this work, we use these features for constructing a prediction model that evaluates the HY stage and the UPDRS scores. A multi-class support vector machine (SVM) classifier is trained using re-sampling approaches such as adaptive synthetic sampling approach (ADASYN). The classifier is evaluated with 4-fold cross validation. The experiments show that HY stage, UPDRS scores, and total UPDRS can be predicted with accuracies of 94%, 92%, and 88% respectively. The proposed method can be implemented as an efficient clinical decision support system for early detection and monitoring the progression of PD.

Original languageEnglish
Title of host publication2nd IEEE International Workshop on Arabic and Derived Script Analysis and Recognition, ASAR 2018
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages7-12
Number of pages6
ISBN (Electronic)9781538614594
DOIs
Publication statusPublished - 2 Oct 2018
Externally publishedYes
Event2nd IEEE International Workshop on Arabic and Derived Script Analysis and Recognition, ASAR 2018 - London, United Kingdom
Duration: 12 Mar 201814 Mar 2018

Publication series

Name2nd IEEE International Workshop on Arabic and Derived Script Analysis and Recognition, ASAR 2018

Conference

Conference2nd IEEE International Workshop on Arabic and Derived Script Analysis and Recognition, ASAR 2018
Country/TerritoryUnited Kingdom
CityLondon
Period12/03/1814/03/18

Keywords

  • ADASYN
  • CV
  • H&Y
  • PDMultiMC dataset
  • Parkinson's disease (PD)
  • SVM
  • UPDRS
  • handwriting

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