Acceleration of nucleophilic CH activation by strongly basic solvents

Brian G. Hashiguchi; Kenneth J.H. Young; Muhammed Yousufuddin; William A. Goddard; Roy A. Periana

doi:10.1021/ja102518m

Acceleration of nucleophilic CH activation by strongly basic solvents

Brian G. Hashiguchi
, Kenneth J.H. Young
, Muhammed Yousufuddin
, William A. Goddard
, Roy A. Periana

Research output: Contribution to journal › Article › peer-review

Abstract

(IPI)Ru(II)(OH)_n(H₂O)_m, 2, where IPI is the NNN-pincer ligand, 2,6-diimidizoylpyridine, is shown to catalyze H/D exchange between hydrocarbons and strongly basic solvents at higher rates than in the case of the solvent alone. Significantly, catalysis by 2 is accelerated rather than inhibited by increasing solvent basicity. The evidence is consistent with the reaction proceeding by base modulated nucleophilic CH activation.

Original language	English
Pages (from-to)	12542-12545
Number of pages	4
Journal	Journal of the American Chemical Society
Volume	132
Issue number	36
DOIs	https://doi.org/10.1021/ja102518m
Publication status	Published - 15 Sept 2010
Externally published	Yes

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10.1021/ja102518m

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title = "Acceleration of nucleophilic CH activation by strongly basic solvents",

abstract = "(IPI)Ru(II)(OH)n(H2O)m, 2, where IPI is the NNN-pincer ligand, 2,6-diimidizoylpyridine, is shown to catalyze H/D exchange between hydrocarbons and strongly basic solvents at higher rates than in the case of the solvent alone. Significantly, catalysis by 2 is accelerated rather than inhibited by increasing solvent basicity. The evidence is consistent with the reaction proceeding by base modulated nucleophilic CH activation.",

author = "Hashiguchi, \{Brian G.\} and Young, \{Kenneth J.H.\} and Muhammed Yousufuddin and Goddard, \{William A.\} and Periana, \{Roy A.\}",

year = "2010",

month = sep,

day = "15",

doi = "10.1021/ja102518m",

language = "English",

volume = "132",

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journal = "Journal of the American Chemical Society",

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AU - Hashiguchi, Brian G.

AU - Young, Kenneth J.H.

AU - Yousufuddin, Muhammed

AU - Goddard, William A.

AU - Periana, Roy A.

PY - 2010/9/15

Y1 - 2010/9/15

N2 - (IPI)Ru(II)(OH)n(H2O)m, 2, where IPI is the NNN-pincer ligand, 2,6-diimidizoylpyridine, is shown to catalyze H/D exchange between hydrocarbons and strongly basic solvents at higher rates than in the case of the solvent alone. Significantly, catalysis by 2 is accelerated rather than inhibited by increasing solvent basicity. The evidence is consistent with the reaction proceeding by base modulated nucleophilic CH activation.

AB - (IPI)Ru(II)(OH)n(H2O)m, 2, where IPI is the NNN-pincer ligand, 2,6-diimidizoylpyridine, is shown to catalyze H/D exchange between hydrocarbons and strongly basic solvents at higher rates than in the case of the solvent alone. Significantly, catalysis by 2 is accelerated rather than inhibited by increasing solvent basicity. The evidence is consistent with the reaction proceeding by base modulated nucleophilic CH activation.

UR - https://www.scopus.com/pages/publications/77956421310

U2 - 10.1021/ja102518m

DO - 10.1021/ja102518m

M3 - Article

C2 - 20734988

AN - SCOPUS:77956421310

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SP - 12542

EP - 12545

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 36

ER -

Acceleration of nucleophilic CH activation by strongly basic solvents

Abstract

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