Access to new endoperoxide derivatives by electrochemical oxidation of substituted 3-azabicyclo[4.1.0]hept-4-enes

Frédérick Nuter; Abdou Khadre Djily Dimé; Cheng Chen; Lotfi Bounaadja; Elisabeth Mouray; Isabelle Florent; Yvan Six; Olivier Buriez; Angela Marinetti; Arnaud Voituriez

doi:10.1002/chem.201406138

Access to new endoperoxide derivatives by electrochemical oxidation of substituted 3-azabicyclo[4.1.0]hept-4-enes

Frédérick Nuter
, Abdou Khadre Djily Dimé
, Cheng Chen
, Lotfi Bounaadja
, Elisabeth Mouray
, Isabelle Florent
, Yvan Six
, Olivier Buriez
, Angela Marinetti
, Arnaud Voituriez

Centre national de la recherche scientifique
Sorbonne Université
Laboratoire de Synthèse Organique
Molécules de Communication et Adaptation des Microorganismes (MCAM

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

A series of substituted 3-azabicyclo[4.1.0]hept-4-ene derivatives were prepared and analysed by cyclic voltammetry. Preparative aerobic electrochemical oxidation reactions were then carried out. Three original endoperoxides were isolated, characterised and subjected to antimalarial and cytotoxicity activity assays.

Original language	English
Pages (from-to)	5584-5593
Number of pages	10
Journal	Chemistry - A European Journal
Volume	21
Issue number	14
DOIs	https://doi.org/10.1002/chem.201406138
Publication status	Published - 27 Mar 2015
Externally published	Yes

Keywords

anti-plasmodial activity
catalysis
cycloisomerization
electrochemistry
endoperoxides

Access to Document

10.1002/chem.201406138

Cite this

@article{150b29e998c84aabb36b5689385e4832,

title = "Access to new endoperoxide derivatives by electrochemical oxidation of substituted 3-azabicyclo[4.1.0]hept-4-enes",

abstract = "A series of substituted 3-azabicyclo[4.1.0]hept-4-ene derivatives were prepared and analysed by cyclic voltammetry. Preparative aerobic electrochemical oxidation reactions were then carried out. Three original endoperoxides were isolated, characterised and subjected to antimalarial and cytotoxicity activity assays.",

keywords = "anti-plasmodial activity, catalysis, cycloisomerization, electrochemistry, endoperoxides",

author = "Fr{\'e}d{\'e}rick Nuter and Dim{\'e}, \{Abdou Khadre Djily\} and Cheng Chen and Lotfi Bounaadja and Elisabeth Mouray and Isabelle Florent and Yvan Six and Olivier Buriez and Angela Marinetti and Arnaud Voituriez",

note = "Publisher Copyright: {\textcopyright} 2015 WILEY-VCH Verlag GmbH \& Co. KGaA, Weinheim.",

year = "2015",

month = mar,

day = "27",

doi = "10.1002/chem.201406138",

language = "English",

volume = "21",

pages = "5584--5593",

journal = "Chemistry - A European Journal",

issn = "0947-6539",

publisher = "John Wiley and Sons Inc",

number = "14",

}

TY - JOUR

T1 - Access to new endoperoxide derivatives by electrochemical oxidation of substituted 3-azabicyclo[4.1.0]hept-4-enes

AU - Nuter, Frédérick

AU - Dimé, Abdou Khadre Djily

AU - Chen, Cheng

AU - Bounaadja, Lotfi

AU - Mouray, Elisabeth

AU - Florent, Isabelle

AU - Six, Yvan

AU - Buriez, Olivier

AU - Marinetti, Angela

AU - Voituriez, Arnaud

PY - 2015/3/27

Y1 - 2015/3/27

N2 - A series of substituted 3-azabicyclo[4.1.0]hept-4-ene derivatives were prepared and analysed by cyclic voltammetry. Preparative aerobic electrochemical oxidation reactions were then carried out. Three original endoperoxides were isolated, characterised and subjected to antimalarial and cytotoxicity activity assays.

AB - A series of substituted 3-azabicyclo[4.1.0]hept-4-ene derivatives were prepared and analysed by cyclic voltammetry. Preparative aerobic electrochemical oxidation reactions were then carried out. Three original endoperoxides were isolated, characterised and subjected to antimalarial and cytotoxicity activity assays.

KW - anti-plasmodial activity

KW - catalysis

KW - cycloisomerization

KW - electrochemistry

KW - endoperoxides

U2 - 10.1002/chem.201406138

DO - 10.1002/chem.201406138

M3 - Article

AN - SCOPUS:84925132703

SN - 0947-6539

VL - 21

SP - 5584

EP - 5593

JO - Chemistry - A European Journal

JF - Chemistry - A European Journal

IS - 14

ER -

Access to new endoperoxide derivatives by electrochemical oxidation of substituted 3-azabicyclo[4.1.0]hept-4-enes

Abstract

Keywords

Access to Document

Fingerprint

Cite this