Addition of aryl substituants to cyclohexadienyliron electrophiles in the development of routes to C12 central building blocks for alkaloid synthesis

Andrej V. Malkov; Audrey Auffrant; Christophe Renard; Eric Rose; Françoise Rose-Munch; David A. Owen; Elizabeth J. Sandoe; G. Richard Stephenson

doi:10.1016/s0020-1693(99)00390-4

Addition of aryl substituants to cyclohexadienyliron electrophiles in the development of routes to C₁₂ central building blocks for alkaloid synthesis

Andrej V. Malkov
, Audrey Auffrant
, Christophe Renard
, Eric Rose
, Françoise Rose-Munch
, David A. Owen
, Elizabeth J. Sandoe
, G. Richard Stephenson

University of East Anglia
Sorbonne Université

Research output: Contribution to journal › Article › peer-review

Abstract

Novel iron-aroyl complexes or synthetically prized arylcyclohexadienyl complexes can be formed from tricarbonyl(η⁵-1,4-dimethoxycyclohexadienyl)iron(1 +) hexafluorophosphate(1-) by correct control of reaction sequences that exploit the addition of aryllithium reagents to introduce the aromatic group. Bimetallic products are obtained when a tricarbonylchromium-bound aryllithium reagent or the corresponding cuprate are employed.

Original language	English
Pages (from-to)	139-149
Number of pages	11
Journal	Inorganica Chimica Acta
Volume	296
Issue number	1
DOIs	https://doi.org/10.1016/s0020-1693(99)00390-4
Publication status	Published - 15 Dec 1999

Keywords

(Aryllithium)chromium complexes
Acyliron complexes
Alkaloid synthesis
Aryllithium nucleophiles
Cyclohexadienyliron electrophiles

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10.1016/s0020-1693(99)00390-4

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title = "Addition of aryl substituants to cyclohexadienyliron electrophiles in the development of routes to C12 central building blocks for alkaloid synthesis",

abstract = "Novel iron-aroyl complexes or synthetically prized arylcyclohexadienyl complexes can be formed from tricarbonyl(η5-1,4-dimethoxycyclohexadienyl)iron(1 +) hexafluorophosphate(1-) by correct control of reaction sequences that exploit the addition of aryllithium reagents to introduce the aromatic group. Bimetallic products are obtained when a tricarbonylchromium-bound aryllithium reagent or the corresponding cuprate are employed.",

keywords = "(Aryllithium)chromium complexes, Acyliron complexes, Alkaloid synthesis, Aryllithium nucleophiles, Cyclohexadienyliron electrophiles",

author = "Malkov, \{Andrej V.\} and Audrey Auffrant and Christophe Renard and Eric Rose and Fran{\c c}oise Rose-Munch and Owen, \{David A.\} and Sandoe, \{Elizabeth J.\} and Stephenson, \{G. Richard\}",

year = "1999",

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doi = "10.1016/s0020-1693(99)00390-4",

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TY - JOUR

T1 - Addition of aryl substituants to cyclohexadienyliron electrophiles in the development of routes to C12 central building blocks for alkaloid synthesis

AU - Malkov, Andrej V.

AU - Auffrant, Audrey

AU - Renard, Christophe

AU - Rose, Eric

AU - Rose-Munch, Françoise

AU - Owen, David A.

AU - Sandoe, Elizabeth J.

AU - Stephenson, G. Richard

PY - 1999/12/15

Y1 - 1999/12/15

N2 - Novel iron-aroyl complexes or synthetically prized arylcyclohexadienyl complexes can be formed from tricarbonyl(η5-1,4-dimethoxycyclohexadienyl)iron(1 +) hexafluorophosphate(1-) by correct control of reaction sequences that exploit the addition of aryllithium reagents to introduce the aromatic group. Bimetallic products are obtained when a tricarbonylchromium-bound aryllithium reagent or the corresponding cuprate are employed.

AB - Novel iron-aroyl complexes or synthetically prized arylcyclohexadienyl complexes can be formed from tricarbonyl(η5-1,4-dimethoxycyclohexadienyl)iron(1 +) hexafluorophosphate(1-) by correct control of reaction sequences that exploit the addition of aryllithium reagents to introduce the aromatic group. Bimetallic products are obtained when a tricarbonylchromium-bound aryllithium reagent or the corresponding cuprate are employed.

KW - (Aryllithium)chromium complexes

KW - Acyliron complexes

KW - Alkaloid synthesis

KW - Aryllithium nucleophiles

KW - Cyclohexadienyliron electrophiles

UR - https://www.scopus.com/pages/publications/0000361497

U2 - 10.1016/s0020-1693(99)00390-4

DO - 10.1016/s0020-1693(99)00390-4

M3 - Article

AN - SCOPUS:0000361497

SN - 0020-1693

VL - 296

SP - 139

EP - 149

JO - Inorganica Chimica Acta

JF - Inorganica Chimica Acta

IS - 1

ER -

Addition of aryl substituants to cyclohexadienyliron electrophiles in the development of routes to C₁₂ central building blocks for alkaloid synthesis

Abstract

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