Analysis of a population model structured by the cells molecular content

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Abstract

We study the mathematical properties of a general model of cell division structured with several internal variables. We begin with a simpler and specific model with two variables, we solve the eigenvalue problem with strong or weak assumptions, and deduce from it the long-time convergence. The main difficulty comes from natural degeneracy of birth terms that we overcome with a regularization technique. We then extend the results to the case with several parameters and recall the link between this simplified model and the one presented in [6]; an application to the non-linear problem is also given, leading to robust subpolynomial growth of the total population.

Original languageEnglish
Pages (from-to)121-152
Number of pages32
JournalMathematical Modelling of Natural Phenomena
Volume2
Issue number3
DOIs
Publication statusPublished - 1 Jan 2007

Keywords

  • cell division
  • eigenproblem
  • long-time asymptotic
  • relative entropy
  • structured populations
  • transport equation

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