Analysis of slow motions in the micro-millisecond range on domain 1 of annexin I

Matthieu Gallopin; Fran Ochsenbein; Éric Guittet; Carine van Heijenoort

doi:10.1016/j.crci.2003.07.021

Analysis of slow motions in the micro-millisecond range on domain 1 of annexin I

Matthieu Gallopin
, Fran Ochsenbein
, Éric Guittet
, Carine van Heijenoort

Institut de Chimie des Substances Naturelles
Institut Pierre Simon Laplace, CNRS and CEA

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

A preliminary study of the dynamics of the domain 1 of annexin I by Nuclear Magnetic Resonance is presented. The use of ¹⁵ N-relaxation-compensated CPMG experiments allowed us to show the presence of conformational motions in the micro-millisecond range that extend over several segments along the domain. For 14 residues, exchange rate constants could be evaluated, and were found in the range 1300-2500 s^-1.

Original language	English
Pages (from-to)	253-258
Number of pages	6
Journal	Comptes Rendus Chimie
Volume	7
Issue number	3-4
DOIs	https://doi.org/10.1016/j.crci.2003.07.021
Publication status	Published - 1 Mar 2004
Externally published	Yes

Keywords

Annexin
Annexine
Dynamics
Dynamique
Folding
Mouvements lents
N relaxation
NMR
RMN
Repliement
Slow motions
relaxation N

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10.1016/j.crci.2003.07.021

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abstract = "A preliminary study of the dynamics of the domain 1 of annexin I by Nuclear Magnetic Resonance is presented. The use of 15 N-relaxation-compensated CPMG experiments allowed us to show the presence of conformational motions in the micro-millisecond range that extend over several segments along the domain. For 14 residues, exchange rate constants could be evaluated, and were found in the range 1300-2500 s-1.",

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author = "Matthieu Gallopin and Fran Ochsenbein and {\'E}ric Guittet and \{van Heijenoort\}, Carine",

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doi = "10.1016/j.crci.2003.07.021",

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T1 - Analysis of slow motions in the micro-millisecond range on domain 1 of annexin I

AU - Gallopin, Matthieu

AU - Ochsenbein, Fran

AU - Guittet, Éric

AU - van Heijenoort, Carine

PY - 2004/3/1

Y1 - 2004/3/1

N2 - A preliminary study of the dynamics of the domain 1 of annexin I by Nuclear Magnetic Resonance is presented. The use of 15 N-relaxation-compensated CPMG experiments allowed us to show the presence of conformational motions in the micro-millisecond range that extend over several segments along the domain. For 14 residues, exchange rate constants could be evaluated, and were found in the range 1300-2500 s-1.

AB - A preliminary study of the dynamics of the domain 1 of annexin I by Nuclear Magnetic Resonance is presented. The use of 15 N-relaxation-compensated CPMG experiments allowed us to show the presence of conformational motions in the micro-millisecond range that extend over several segments along the domain. For 14 residues, exchange rate constants could be evaluated, and were found in the range 1300-2500 s-1.

KW - Annexin

KW - Annexine

KW - Dynamics

KW - Dynamique

KW - Folding

KW - Mouvements lents

KW - N relaxation

KW - NMR

KW - RMN

KW - Repliement

KW - Slow motions

KW - relaxation N

UR - https://www.scopus.com/pages/publications/2342593202

U2 - 10.1016/j.crci.2003.07.021

DO - 10.1016/j.crci.2003.07.021

M3 - Article

AN - SCOPUS:2342593202

SN - 1631-0748

VL - 7

SP - 253

EP - 258

JO - Comptes Rendus Chimie

JF - Comptes Rendus Chimie

IS - 3-4

ER -

Analysis of slow motions in the micro-millisecond range on domain 1 of annexin I

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Keywords

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