Apport de l'imagerie par spectrométrie de masse pour l'analyse directe du globotriaosylcéramide et du galabiosylcéramide tissulaires

Sandrine Roy; David Touboul; Alain Brunelle; Dominique P. Germain; Olivier Laprévote; Pierre Chaminade

doi:10.1051/medsci/20052111s55

Apport de l'imagerie par spectrométrie de masse pour l'analyse directe du globotriaosylcéramide et du galabiosylcéramide tissulaires

Translated title of the contribution: Imaging mass spectrometry and direct analysis of globotriaosylceramide and galabiosylceramide in tissue

Sandrine Roy
, David Touboul
, Alain Brunelle
, Dominique P. Germain
, Olivier Laprévote
, Pierre Chaminade

Faculté de Pharmacie Paris XI
Institut de Chimie des Substances Naturelles
Pôle de Biologie

Research output: Contribution to journal › Article › peer-review

Abstract

In Fabry disease, accumulation of globotrianosylceramide and galabiosylceramide are observed by coloration methods associated to optic or electron microscopy. But a new technology, imaging mass spectrometry, may be applied to the analysis of these metabolites in tissue of hemizygous patients with Fabry disease. Advantages and disavantadges of this technic are discussed.

Translated title of the contribution	Imaging mass spectrometry and direct analysis of globotriaosylceramide and galabiosylceramide in tissue
Original language	French
Pages (from-to)	55-56
Number of pages	2
Journal	Medecine/Sciences
Volume	21
Issue number	SPEC. ISS. NOV.
DOIs	https://doi.org/10.1051/medsci/20052111s55
Publication status	Published - 1 Jan 2005
Externally published	Yes

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title = "Apport de l'imagerie par spectrom{\'e}trie de masse pour l'analyse directe du globotriaosylc{\'e}ramide et du galabiosylc{\'e}ramide tissulaires",

abstract = "In Fabry disease, accumulation of globotrianosylceramide and galabiosylceramide are observed by coloration methods associated to optic or electron microscopy. But a new technology, imaging mass spectrometry, may be applied to the analysis of these metabolites in tissue of hemizygous patients with Fabry disease. Advantages and disavantadges of this technic are discussed.",

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AU - Roy, Sandrine

AU - Touboul, David

AU - Brunelle, Alain

AU - Germain, Dominique P.

AU - Laprévote, Olivier

AU - Chaminade, Pierre

PY - 2005/1/1

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AB - In Fabry disease, accumulation of globotrianosylceramide and galabiosylceramide are observed by coloration methods associated to optic or electron microscopy. But a new technology, imaging mass spectrometry, may be applied to the analysis of these metabolites in tissue of hemizygous patients with Fabry disease. Advantages and disavantadges of this technic are discussed.

U2 - 10.1051/medsci/20052111s55

DO - 10.1051/medsci/20052111s55

M3 - Article

AN - SCOPUS:29944435231

SN - 0767-0974

VL - 21

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JO - Medecine/Sciences

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IS - SPEC. ISS. NOV.

ER -

Apport de l'imagerie par spectrométrie de masse pour l'analyse directe du globotriaosylcéramide et du galabiosylcéramide tissulaires

Abstract

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