Artifact-free balanced detection for the measurement of circular dichroism with a sub-picosecond time resolution

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Abstract

We present the development of a subpicosecond spectropolarimeter enabling high sensitivity balanced detection of time-resolved circular dichroism (TRCD) signals from chiral sample in solution. The signals are measured with a conventional femtosecond pump-probe set-up using the combination of a quarter-waveplate and a Wollaston prism. This simple and robust method allows access to TRCD signals with improved signal-to-noise ratio and very short acquisition times. We provide a theoretical analysis of the artifacts of such detection geometry and the strategy to eliminate them. We illustrate the potential of this new detection with the study of the [Ru(phen)3]·2PF6 complexes in acetonitrile.

Original languageEnglish
Title of host publicationPolarized Light and Optical Angular Momentum for Biomedical Diagnostics 2024
EditorsJessica C. Ramella-Roman, Hui Ma, Tatiana Novikova, Daniel S. Elson, I. Alex Vitkin
PublisherSPIE
ISBN (Electronic)9781510669499
DOIs
Publication statusPublished - 1 Jan 2024
EventPolarized Light and Optical Angular Momentum for Biomedical Diagnostics 2024 - San Francisco, United States
Duration: 27 Jan 202428 Jan 2024

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume12845
ISSN (Print)1605-7422

Conference

ConferencePolarized Light and Optical Angular Momentum for Biomedical Diagnostics 2024
Country/TerritoryUnited States
CitySan Francisco
Period27/01/2428/01/24

Keywords

  • balanced detection
  • time-resolved circular dichroism

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