Automatically Generated Cardiovascular Digital Twin in Critical Care: A Proof of Concept Study

François Kimmig, Arthur Le Gall, Camille Windsor, Fabrice Vallée, Dominique Chapelle, Philippe Moireau

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

This proof of concept study demonstrates the capabilities of a virtually automatically generated digital twin framework for enhancing hemodynamic monitoring in critical care. By combining a deterministic cardiovascular model with patient-specific data through data assimilation techniques, the digital twin can act as a data denoiser, reconstruct physiological waveforms that are typically unavailable in critical care settings and generate clinically relevant biomarkers. Validation was performed using real data from patients under general anesthesia. The proposed framework efficient calibration and ability to follow the patient’s state over time supports the possibility of real-time bedside applications.

Original languageEnglish
Title of host publicationFunctional Imaging and Modeling of the Heart - 13th International Conference, FIMH 2025, Proceedings
EditorsRadomír Chabiniok, Qing Zou, Tarique Hussain, Hoang H. Nguyen, Vlad G. Zaha, Maria Gusseva
PublisherSpringer Science and Business Media Deutschland GmbH
Pages384-396
Number of pages13
ISBN (Print)9783031945618
DOIs
Publication statusPublished - 1 Jan 2025
Event13th International Conference on Functional Imaging and Modeling of the Heart, FIMH 2025 - Dallas, United States
Duration: 1 Jun 20255 Jun 2025

Publication series

NameLecture Notes in Computer Science
Volume15673 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference13th International Conference on Functional Imaging and Modeling of the Heart, FIMH 2025
Country/TerritoryUnited States
CityDallas
Period1/06/255/06/25

Keywords

  • Cardiovascular
  • Critical care monitoring
  • Digital twin
  • Model-data interaction

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