Capillary muscle

Caroline Cohen; Timothée Mouterde; David Quéré; Christophe Clanet

doi:10.1073/pnas.1419315112

Capillary muscle

UMR 7636 CNRS-ESPCI ParisTech-Université Pierre et Marie Curie
Laboratoire d'Hydrodynamique de l'Ecole Polytechnique

Research output: Contribution to journal › Article › peer-review

Abstract

The contraction of a muscle generates a force that decreases when increasing the contraction velocity. This "hyperbolic" force-velocity relationship has been known since the seminal work of A. V. Hill in 1938 [Hill AV (1938) Proc R Soc Lond B Biol Sci 126(843):136-195]. Hill's heuristic equation is still used, and the sliding-filament theory for the sarcomere [Huxley H, Hanson J (1954) Nature 173 (4412):973-976; Huxley AF, Niedergerke R (1954) Nature 173 (4412):971-973] suggested how its different parameters can be related to the molecular origin of the force generator [Huxley AF (1957) Prog Biophys Biophys Chem 7:255-318; Deshcherevski? VI (1968) Biofizika 13(5):928-935]. Here, we develop a capillary analog of the sarcomere obeying Hill's equation and discuss its analogy with muscles.

Original language	English
Pages (from-to)	6301-6306
Number of pages	6
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	112
Issue number	20
DOIs	https://doi.org/10.1073/pnas.1419315112
Publication status	Published - 19 May 2015

Keywords

Capillary |force-velocity relation
Muscle contraction
Sliding |actomyosin cycle

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10.1073/pnas.1419315112

Cite this

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title = "Capillary muscle",

abstract = "The contraction of a muscle generates a force that decreases when increasing the contraction velocity. This {"}hyperbolic{"} force-velocity relationship has been known since the seminal work of A. V. Hill in 1938 [Hill AV (1938) Proc R Soc Lond B Biol Sci 126(843):136-195]. Hill's heuristic equation is still used, and the sliding-filament theory for the sarcomere [Huxley H, Hanson J (1954) Nature 173 (4412):973-976; Huxley AF, Niedergerke R (1954) Nature 173 (4412):971-973] suggested how its different parameters can be related to the molecular origin of the force generator [Huxley AF (1957) Prog Biophys Biophys Chem 7:255-318; Deshcherevski? VI (1968) Biofizika 13(5):928-935]. Here, we develop a capillary analog of the sarcomere obeying Hill's equation and discuss its analogy with muscles.",

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doi = "10.1073/pnas.1419315112",

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T1 - Capillary muscle

AU - Cohen, Caroline

AU - Mouterde, Timothée

AU - Quéré, David

AU - Clanet, Christophe

PY - 2015/5/19

Y1 - 2015/5/19

N2 - The contraction of a muscle generates a force that decreases when increasing the contraction velocity. This "hyperbolic" force-velocity relationship has been known since the seminal work of A. V. Hill in 1938 [Hill AV (1938) Proc R Soc Lond B Biol Sci 126(843):136-195]. Hill's heuristic equation is still used, and the sliding-filament theory for the sarcomere [Huxley H, Hanson J (1954) Nature 173 (4412):973-976; Huxley AF, Niedergerke R (1954) Nature 173 (4412):971-973] suggested how its different parameters can be related to the molecular origin of the force generator [Huxley AF (1957) Prog Biophys Biophys Chem 7:255-318; Deshcherevski? VI (1968) Biofizika 13(5):928-935]. Here, we develop a capillary analog of the sarcomere obeying Hill's equation and discuss its analogy with muscles.

AB - The contraction of a muscle generates a force that decreases when increasing the contraction velocity. This "hyperbolic" force-velocity relationship has been known since the seminal work of A. V. Hill in 1938 [Hill AV (1938) Proc R Soc Lond B Biol Sci 126(843):136-195]. Hill's heuristic equation is still used, and the sliding-filament theory for the sarcomere [Huxley H, Hanson J (1954) Nature 173 (4412):973-976; Huxley AF, Niedergerke R (1954) Nature 173 (4412):971-973] suggested how its different parameters can be related to the molecular origin of the force generator [Huxley AF (1957) Prog Biophys Biophys Chem 7:255-318; Deshcherevski? VI (1968) Biofizika 13(5):928-935]. Here, we develop a capillary analog of the sarcomere obeying Hill's equation and discuss its analogy with muscles.

KW - Capillary |force-velocity relation

KW - Muscle contraction

KW - Sliding |actomyosin cycle

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Capillary muscle

Abstract

Keywords

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