@inproceedings{2d19a1424a2c4625bf70627200637e17,
title = "Chiral chromophores for second harmonic microscopy",
abstract = "The use of chiral harmonophores in second harmonic generation (SHG) microscopy of lipid bila yers should enable one to obtain a signal even when the distribution of the chromophores is centrosymmetric. In order to determine optimal chiral molecules, we performed polarization-resolved second harmonic re ection experiments. We found that chirality must arise from an excitonic coupling rather than from an asymmetric center. We selectively labeled giant unilamellar lipid vesicles and cell membranes with such a molecule, namely an acridine substituted Tr{\"o}ger's base, as demonstrated by two-photon-excited uorescence microscopy. We performed preliminary SHG microscopy experiments, but the poor efficiency of the current form of our molecule does not allow us to demonstrate chirality effects.",
keywords = "Nonlinear microscopy, chirality, giant unilamellar vesicles, lipid membranes, second harmonic generation",
author = "Schanne-Klein, \{M. C.\} and T. Boulesteix and E. Beaurepaire and Sauviat, \{M. P.\}",
note = "Publisher Copyright: {\textcopyright} 2003 SPIE-OSA.; European Conference on Biomedical Optics, ECBO 2003 ; Conference date: 22-06-2003",
year = "2003",
month = jan,
day = "1",
language = "English",
series = "Optics InfoBase Conference Papers",
publisher = "Optica Publishing Group (formerly OSA)",
pages = "121--128",
booktitle = "European Conference on Biomedical Optics, ECBO 2003",
}