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Circular-dichroism SHG microscopy probes the polarity distribution of out-of-plane collagen fibril assemblies

  • Margaux Schmeltz
  • , Claire Teulon
  • , Maxime Pinsard
  • , Uwe Hansen
  • , Maged Alnawaiseh
  • , Djida Ghoubay
  • , Vincent Borderie
  • , Gervaise Mosser
  • , Carole Aime
  • , Francois Legare
  • , Gael Latour
  • , Marie Claire Schanne-Klein
  • INRS-ÉMT
  • University of Münster
  • University of Münster
  • Sorbonne Université
  • Université Paris-Saclay

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Second harmonic generation microscopy (SHG) is now the gold standard technique for in situ visualization of unstained fibrillar collagen in intact tissues [1]. Collagen is the most abundant protein in mammals and is found in many tissues, such as arteries, skin, bone and cornea. The size and the three-dimensional distribution of collagen fibrils are key distinctive features of every tissue that are crucial for its functional behaviour, notably its mechanical properties. In situ characterization of collagen 3D distribution is therefore a major biomedical challenge.

Original languageEnglish
Title of host publication2021 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2021
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781665418768
DOIs
Publication statusPublished - 1 Jun 2021
Event2021 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2021 - Munich, Germany
Duration: 21 Jun 202125 Jun 2021

Publication series

Name2021 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2021

Conference

Conference2021 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2021
Country/TerritoryGermany
CityMunich
Period21/06/2125/06/21

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