Complete nucleotide sequence of plasmid pTN48, encoding the CTX-M-14 extended-spectrum β-lactamase from an Escherichia coli O102-ST405 strain

Typhaine Billard-Pomares, Olivier Tenaillon, Hervé Le Nagard, Zoé Rouy, Stéphane Cruveiller, Claudine Médigue, Guillaume Arlet, Erick Denamur, Catherine Branger

Research output: Contribution to journalArticlepeer-review

Abstract

The sequence of pTN48, a plasmid of the FII-FIB replicon type that encodes a CTX-M-14 enzyme in an Escherichia coli strain of the phylogenetic group D 2 O102-ST405 clone, was determined. pTN48 is, for the most part, a mosaic of virulence, antibiotic resistance, and addiction system modules found in various other plasmids. The presence of multiple addiction systems indicates that the plasmid should be stably maintained in the E. coli clone, favoring dissemination of the CTX-M-14 enzyme.

Original languageEnglish
Pages (from-to)1270-1273
Number of pages4
JournalAntimicrobial Agents and Chemotherapy
Volume55
Issue number3
DOIs
Publication statusPublished - 1 Jan 2011
Externally publishedYes

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