Confinement and time immemorial: prebiotic synthesis of nucleotides on a porous mineral nanoreactor

  • Francisco Rodrigues
  • , Thomas Georgelin
  • , Guillaume Gabant
  • , Baptiste Rigaud
  • , Fabrice Gaslain
  • , Guanzheng Zhuang
  • , Maria Gardênnia Da Fonseca
  • , Valentin Valtchev
  • , David Touboul
  • , Maguy Jaber

Research output: Contribution to journalArticlepeer-review

Abstract

We report the successful one-pot synthesis of adenosine mono-, di-, and triphosphate in the confined space of a mordenite zeolite. This is also the first report of ATP synthesized onto a porous mineral surface. The results revealed a plausible prebiotic route to ribonucleotides and highlighted the contribution of microporous minerals in the origins of life.

Original languageEnglish
Pages (from-to)4192-4196
Number of pages5
JournalJournal of Physical Chemistry Letters
Volume10
Issue number15
DOIs
Publication statusPublished - 1 Aug 2019
Externally publishedYes

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