Connecting membrane traffic to ESCRT and the final cut

Research output: Contribution to journalArticlepeer-review

Abstract

The ESCRT (endosomal sorting complex required for transport) machinery is responsible for scission of the cytokinetic bridge that connects daughter cells at the end of mitosis. Specific endosomes are now found to mediate local bridge constriction and actin clearance in human cells, which contribute to the recruitment of ESCRT components at the abscission site.

Original languageEnglish
Pages (from-to)983-985
Number of pages3
JournalNature Cell Biology
Volume14
Issue number10
DOIs
Publication statusPublished - 1 Oct 2012
Externally publishedYes

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