Abstract
Copper-catalyzed Sonogashira reaction has been realized under biphasic conditions (water / organic substrates) allowing decreasing the copper loading up to 0.02–0.2 mol %. A potential intermediate species of the reaction, corresponding to a copper cluster linked with acetylide moiety, has been identified.
| Original language | English |
|---|---|
| Pages (from-to) | 11599-11602 |
| Number of pages | 4 |
| Journal | ChemistrySelect |
| Volume | 2 |
| Issue number | 35 |
| DOIs | |
| Publication status | Published - 11 Dec 2017 |
| Externally published | Yes |
Keywords
- Sonogashira
- copper-catalyzed
- mechanism
- turn-over
- water