Deep mutational scans clarify the record of evolution

Manolo Mischler; Olivier Tenaillon

doi:10.1038/s41559-025-02902-5

Deep mutational scans clarify the record of evolution

Manolo Mischler
, Olivier Tenaillon

Institut Cochin

Research output: Contribution to journal › Comment/debate

Abstract

Population genetics simulations and experimental evolution in yeast reconcile the apparent contradiction between high levels of beneficial mutations observed in the laboratory and long-term evolutionary patterns that mimic neutrality.

Original language	English
Pages (from-to)	2189-2190
Number of pages	2
Journal	Nature Ecology and Evolution
Volume	9
Issue number	12
DOIs	https://doi.org/10.1038/s41559-025-02902-5
Publication status	Published - 1 Dec 2025
Externally published	Yes

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title = "Deep mutational scans clarify the record of evolution",

abstract = "Population genetics simulations and experimental evolution in yeast reconcile the apparent contradiction between high levels of beneficial mutations observed in the laboratory and long-term evolutionary patterns that mimic neutrality.",

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AU - Tenaillon, Olivier

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N2 - Population genetics simulations and experimental evolution in yeast reconcile the apparent contradiction between high levels of beneficial mutations observed in the laboratory and long-term evolutionary patterns that mimic neutrality.

AB - Population genetics simulations and experimental evolution in yeast reconcile the apparent contradiction between high levels of beneficial mutations observed in the laboratory and long-term evolutionary patterns that mimic neutrality.

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AN - SCOPUS:105021819807

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JO - Nature Ecology and Evolution

JF - Nature Ecology and Evolution

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Deep mutational scans clarify the record of evolution

Abstract

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