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Diagnostics of high grade cervical intraepithelial neoplasia with Mueller matrix polarimetry

  • Université Paris-Saclay
  • University of Arizona
  • Institut d’Optique Graduate School

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

An enhancement of contrast between healthy and neoplastic zones in Mueller matrix images of excised cervical tissue was demonstrated in our prior work for the visible wavelength range. In this paper we present the statistical analysis of Mueller polarimetric data for the diagnostics of high grade cervical intraepithelial neoplasia. The results of linear and non-linear post-processing compressions of the full Mueller matrix are discussed and compared in terms of diagnostic performance. The final goal of these studies is to estimate and compare the diagnostic usefulness of 16 polarimetric measurements required for the reconstruction of complete Mueller matrix of a sample, while looking for an optimal design of future imaging protocols.

Original languageEnglish
Title of host publicationEuropean Conference on Biomedical Optics, ECBO_2019
PublisherOptica Publishing Group (formerly OSA)
ISBN (Print)9781510628397
DOIs
Publication statusPublished - 1 Jan 2019
Externally publishedYes
EventEuropean Conference on Biomedical Optics, ECBO_2019 - Munich, Netherlands
Duration: 23 Jun 201925 Jun 2019

Publication series

NameOptics InfoBase Conference Papers
VolumePart F142-ECBO 2019
ISSN (Electronic)2162-2701

Conference

ConferenceEuropean Conference on Biomedical Optics, ECBO_2019
Country/TerritoryNetherlands
CityMunich
Period23/06/1925/06/19

Keywords

  • Cervical intraepithelial neoplasia
  • Mueller matrix imaging
  • Optical biopsy
  • Post-processing of polarimetric data
  • Statistical analysis

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