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Differentiation of collagen-related skin diseases through polarimetry and fluorescence

  • Tsanislava I. Genova
  • , Deyan D. Ivanov
  • , Lidia B. Zaharieva
  • , Victoria S. Mircheva
  • , Tatiana Novikova
  • , Razvigor Ossikovski
  • , Petranka P. Troyanova
  • Institute of Electronics Bulgarian Academy of Sciences
  • Institut polytechnique de Paris
  • Tsaritsa Yoanna-ISUL University Hospital

Research output: Contribution to conferencePaperpeer-review

Abstract

Diagnosis of degenerative collagen-related skin diseases is a complex process that requires histopathological evaluation of various pathological alterations, which in addition are not unambiguous in themselves. Fluorescence spectroscopy has proven to be valuable tool for tissue differentiation, whereas the biomedical application of tissue polarimetry is establishing as a valuable diagnostic modality. In this work we present the evaluation of experimental results of histology tissue slides from three collagen-related skin diseases: psoriasis, lupus and scleroderma, through fluorescence spectroscopy and Muller polarimetry.

Original languageEnglish
DOIs
Publication statusPublished - 1 Jan 2023
Event2023 European Conference on Biomedical Optics, ECBO 2023 - Munich, Germany
Duration: 25 Jun 202329 Jun 2023

Conference

Conference2023 European Conference on Biomedical Optics, ECBO 2023
Country/TerritoryGermany
CityMunich
Period25/06/2329/06/23

Keywords

  • fluorescence
  • lupus
  • polarimetry
  • psoriasis
  • scleroderma
  • tissue slides

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