(Diphosphine)Nickel-catalyzed negishi cross-coupling: An experimental and theoretical study

Emmanuel Nicolas; Alexia Ohleier; Florian D'Accriscio; Anne Frédérique Pécharman; Matthieu Demange; Philippe Ribagnac; Jorge Ballester; Corinne Gosmini; Nicolas Mézailles

doi:10.1002/chem.201500192

(Diphosphine)Nickel-catalyzed negishi cross-coupling: An experimental and theoretical study

Emmanuel Nicolas
, Alexia Ohleier
, Florian D'Accriscio
, Anne Frédérique Pécharman
, Matthieu Demange
, Philippe Ribagnac
, Jorge Ballester
, Corinne Gosmini
, Nicolas Mézailles

CNRS
Centre national de la recherche scientifique

Research output: Contribution to journal › Article › peer-review

Abstract

The use of a strongly donating "(bis-dialkylphosphine)Ni" fragment promotes the catalytic coupling of a large range of ArCl and ArZnCl derivatives under mild conditions. Stoichiometric mechanistic investigations and DFT calculations prove that a Ni⁰/Ni^II cycle is operative in this system.

Original language	English
Pages (from-to)	7690-7694
Number of pages	5
Journal	Chemistry - A European Journal
Volume	21
Issue number	21
DOIs	https://doi.org/10.1002/chem.201500192
Publication status	Published - 18 May 2015
Externally published	Yes

Keywords

Negishi coupling
Ni catalysis
cross-coupling
dft
diphosphine ligands
mechanistic study

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10.1002/chem.201500192

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title = "(Diphosphine)Nickel-catalyzed negishi cross-coupling: An experimental and theoretical study",

abstract = "The use of a strongly donating {"}(bis-dialkylphosphine)Ni{"} fragment promotes the catalytic coupling of a large range of ArCl and ArZnCl derivatives under mild conditions. Stoichiometric mechanistic investigations and DFT calculations prove that a Ni0/NiII cycle is operative in this system.",

keywords = "Negishi coupling, Ni catalysis, cross-coupling, dft, diphosphine ligands, mechanistic study",

author = "Emmanuel Nicolas and Alexia Ohleier and Florian D'Accriscio and P{\'e}charman, \{Anne Fr{\'e}d{\'e}rique\} and Matthieu Demange and Philippe Ribagnac and Jorge Ballester and Corinne Gosmini and Nicolas M{\'e}zailles",

note = "Publisher Copyright: {\textcopyright} 2015 WILEY-VCH Verlag GmbH \& Co. KGaA, Weinheim.",

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month = may,

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doi = "10.1002/chem.201500192",

language = "English",

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T1 - (Diphosphine)Nickel-catalyzed negishi cross-coupling

T2 - An experimental and theoretical study

AU - Nicolas, Emmanuel

AU - Ohleier, Alexia

AU - D'Accriscio, Florian

AU - Pécharman, Anne Frédérique

AU - Demange, Matthieu

AU - Ribagnac, Philippe

AU - Ballester, Jorge

AU - Gosmini, Corinne

AU - Mézailles, Nicolas

PY - 2015/5/18

Y1 - 2015/5/18

N2 - The use of a strongly donating "(bis-dialkylphosphine)Ni" fragment promotes the catalytic coupling of a large range of ArCl and ArZnCl derivatives under mild conditions. Stoichiometric mechanistic investigations and DFT calculations prove that a Ni0/NiII cycle is operative in this system.

AB - The use of a strongly donating "(bis-dialkylphosphine)Ni" fragment promotes the catalytic coupling of a large range of ArCl and ArZnCl derivatives under mild conditions. Stoichiometric mechanistic investigations and DFT calculations prove that a Ni0/NiII cycle is operative in this system.

KW - Negishi coupling

KW - Ni catalysis

KW - cross-coupling

KW - dft

KW - diphosphine ligands

KW - mechanistic study

U2 - 10.1002/chem.201500192

DO - 10.1002/chem.201500192

M3 - Article

AN - SCOPUS:84928951032

SN - 0947-6539

VL - 21

SP - 7690

EP - 7694

JO - Chemistry - A European Journal

JF - Chemistry - A European Journal

IS - 21

ER -

(Diphosphine)Nickel-catalyzed negishi cross-coupling: An experimental and theoretical study

Abstract

Keywords

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