Abstract
In this study, a hydrogenated lecithin-containing nanoemulsion was prepared from hydrogenated lecithin and silicone oil. Tween-60 and liquid paraffin, widely known emulsifiers, were used as standard substances, and high shear was produced by utilizing a high shear homogenizer and microfluidizer. The properties of the nanoemulsion prepared with hydrogenated lecithin were evaluated by measuring interfacial tension, dynamic interfacial tension, droplet size, zeta-potential, friction force, skin surface hygrometery, and dermal safety. The interfacial tension of lecinol S10/silicone oil was lower than that of lecinol S10/liquid paraffin. The nanoemulsion prepared from hydrogenated lecithin shows lower zeta-potential, skin surface hygrometery, and friction force compared with a general emulsion. The silicone nanoemulsion prepared from hydrogenated lecithin showed a zero value in the patch test and thus exhibits high dermal safety.
| Original language | English |
|---|---|
| Pages (from-to) | 821-824 |
| Number of pages | 4 |
| Journal | Bulletin of the Korean Chemical Society |
| Volume | 30 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 1 Jan 2009 |
| Externally published | Yes |
Keywords
- Interfacial tension
- Lecithin
- Nanoemulsion
- Skin safety
- Zeta-potential