Efficient construction of polycyclic alkaloid synthetic precursors by a xanthate free radical addition and Mannich cyclisation cascade

Edward W. Tate; Samir Z. Zard

doi:10.1016/S0040-4039(02)00835-3

Efficient construction of polycyclic alkaloid synthetic precursors by a xanthate free radical addition and Mannich cyclisation cascade

Edward W. Tate
, Samir Z. Zard

Laboratoire de Synthèse Organique

Research output: Contribution to journal › Article › peer-review

Abstract

Routes to synthetic precursors of Lupin and Eburna alkaloids have been developed, featuring the rapid construction of highly functionalised intermediates by the intermolecular radical coupling of xanthates and alkenes, followed by acid-mediated condensation-cyclisation.

Original language	English
Pages (from-to)	4683-4686
Number of pages	4
Journal	Tetrahedron Letters
Volume	43
Issue number	26
DOIs	https://doi.org/10.1016/S0040-4039(02)00835-3
Publication status	Published - 28 Jun 2002
Externally published	Yes

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title = "Efficient construction of polycyclic alkaloid synthetic precursors by a xanthate free radical addition and Mannich cyclisation cascade",

abstract = "Routes to synthetic precursors of Lupin and Eburna alkaloids have been developed, featuring the rapid construction of highly functionalised intermediates by the intermolecular radical coupling of xanthates and alkenes, followed by acid-mediated condensation-cyclisation.",

author = "Tate, \{Edward W.\} and Zard, \{Samir Z.\}",

year = "2002",

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T1 - Efficient construction of polycyclic alkaloid synthetic precursors by a xanthate free radical addition and Mannich cyclisation cascade

AU - Tate, Edward W.

AU - Zard, Samir Z.

PY - 2002/6/28

Y1 - 2002/6/28

N2 - Routes to synthetic precursors of Lupin and Eburna alkaloids have been developed, featuring the rapid construction of highly functionalised intermediates by the intermolecular radical coupling of xanthates and alkenes, followed by acid-mediated condensation-cyclisation.

AB - Routes to synthetic precursors of Lupin and Eburna alkaloids have been developed, featuring the rapid construction of highly functionalised intermediates by the intermolecular radical coupling of xanthates and alkenes, followed by acid-mediated condensation-cyclisation.

UR - https://www.scopus.com/pages/publications/0037189175

U2 - 10.1016/S0040-4039(02)00835-3

DO - 10.1016/S0040-4039(02)00835-3

M3 - Article

AN - SCOPUS:0037189175

SN - 0040-4039

VL - 43

SP - 4683

EP - 4686

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 26

ER -

Efficient construction of polycyclic alkaloid synthetic precursors by a xanthate free radical addition and Mannich cyclisation cascade

Abstract

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