Evolution of genes neighborhood within reconciled phylogenies: An ensemble approach

  • Cedric Chauve
  • , Yann Ponty
  • , João Paulo Pereira Zanetti

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

We consider a recently introduced dynamic programming scheme to compute parsimonious evolutionary scenarios for gene adjacencies. We extend this scheme to sample evolutionary scenarios from the whole solution space under the Boltzmann distribution. We apply our algorithms to a dataset of mammalian gene trees and adjacencies, and observe a significant reduction of the number of syntenic inconsistencies observed in the resulting ancestral gene adjacencies.

Original languageEnglish
Title of host publicationAdvances in Bioinformatics and Computational Biology - 9th Brazilian Symposium on Bioinformatics, BSB 2014, Proceedings
EditorsSérgio Campos
PublisherSpringer Verlag
Pages49-56
Number of pages8
ISBN (Electronic)9783319124179
DOIs
Publication statusPublished - 1 Jan 2014
Externally publishedYes
Event9th Brazilian Symposium on Bioinformatics, BSB 2014 - Belo Horizonte, Brazil
Duration: 28 Oct 201430 Oct 2014

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume8826
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference9th Brazilian Symposium on Bioinformatics, BSB 2014
Country/TerritoryBrazil
CityBelo Horizonte
Period28/10/1430/10/14

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