TY - GEN
T1 - Functionalized luminescent oxide nanoparticles as biological probes
AU - Giaume, Domitille
AU - Casanova, Didier
AU - Lahlil, Khalid
AU - Sauviat, Martin Pierre
AU - Alexandrou, Antigoni
AU - Gacoin, Thierry
AU - Boilot, Jean Pierre
PY - 2006/1/1
Y1 - 2006/1/1
N2 - Synthesis and functionalization of nanoparticles of yttrium vanadate doped with europium is described. Synthesis of yttrium vanadate leads to ovoid nanoparticles, with average length and width respectively of 30 and 18 nm. Dispersion of these nanoparticles in solution is achieved through the adsorption of silicate ions that increase the surface potential. The nanoparticles are then functionalized by encapsulation with an epoxysilane (glycidoxypropyltrimethoxysilane). The functionalization is controlled by 29Si MAS NMR and thermal analysis, whereas a partial opening of the epoxy rings is evidenced by 13C MAS NMR. As an example of application, guanidinium groups were grafted to ensure the specific interactions of the particles with sodium channels of a cell membrane.
AB - Synthesis and functionalization of nanoparticles of yttrium vanadate doped with europium is described. Synthesis of yttrium vanadate leads to ovoid nanoparticles, with average length and width respectively of 30 and 18 nm. Dispersion of these nanoparticles in solution is achieved through the adsorption of silicate ions that increase the surface potential. The nanoparticles are then functionalized by encapsulation with an epoxysilane (glycidoxypropyltrimethoxysilane). The functionalization is controlled by 29Si MAS NMR and thermal analysis, whereas a partial opening of the epoxy rings is evidenced by 13C MAS NMR. As an example of application, guanidinium groups were grafted to ensure the specific interactions of the particles with sodium channels of a cell membrane.
U2 - 10.1557/proc-0942-w12-05
DO - 10.1557/proc-0942-w12-05
M3 - Conference contribution
AN - SCOPUS:33947659572
SN - 1558998993
SN - 9781558998995
T3 - Materials Research Society Symposium Proceedings
SP - 90
EP - 96
BT - Colloidal Materials
PB - Materials Research Society
T2 - 2006 MRS Spring Meeting
Y2 - 18 April 2006 through 21 April 2006
ER -