Hydroxyapatite mineralization on the calcium chloride blended polyurethane nanofiber via biomimetic method

R. Nirmala; Ki Taek Nam; R. Navamathavan; Soo Jin Park; Hak Yong Kim

doi:10.1186/1556-276X-7-2

Hydroxyapatite mineralization on the calcium chloride blended polyurethane nanofiber via biomimetic method

R. Nirmala
, Ki Taek Nam
, R. Navamathavan
, Soo Jin Park
, Hak Yong Kim

Chonbuk National University

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Polyurethane nanofibers containing calcium chloride (CaCl ₂) were prepared via an electrospinning technique for the biomedical applications. Polyurethane nanofibers with different concentration of CaCl ₂ were electrospun, and their bioactivity evaluation was conducted by incubating in biomimetic simulated body fluid (SBF) solution. The morphology, structure and thermal properties of the polyurethane/CaCl ₂ composite nanofibers were characterized by means of scanning electron microscopy (SEM), field-emission scanning electron microscopy, energy dispersive X-ray spectroscopy, X-ray diffraction, Fourier transform infrared spectroscopy and thermogravimetry. SEM images revealed that the CaCl ₂ salt incorporated homogeneously to form well-oriented nanofibers with smooth surface and uniform diameters along their lengths. The SBF incubation test confirmed the formation of apatite-like materials, exhibiting enhanced bioactive behavior of the polyurethane/CaCl ₂ composite nanofibers. This study demonstrated that the electrospun polyurethane containing CaCl ₂ composite nanofibers enhanced the in vitro bioactivity and supports the growth of apatite-like materials.

Original language	English
Article number	2
Pages (from-to)	1-8
Number of pages	8
Journal	Nanoscale Research Letters
Volume	7
DOIs	https://doi.org/10.1186/1556-276X-7-2
Publication status	Published - 26 Jan 2012
Externally published	Yes

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@article{552037761cc54506b9512fd2d3faf383,

title = "Hydroxyapatite mineralization on the calcium chloride blended polyurethane nanofiber via biomimetic method",

abstract = "Polyurethane nanofibers containing calcium chloride (CaCl 2) were prepared via an electrospinning technique for the biomedical applications. Polyurethane nanofibers with different concentration of CaCl 2 were electrospun, and their bioactivity evaluation was conducted by incubating in biomimetic simulated body fluid (SBF) solution. The morphology, structure and thermal properties of the polyurethane/CaCl 2 composite nanofibers were characterized by means of scanning electron microscopy (SEM), field-emission scanning electron microscopy, energy dispersive X-ray spectroscopy, X-ray diffraction, Fourier transform infrared spectroscopy and thermogravimetry. SEM images revealed that the CaCl 2 salt incorporated homogeneously to form well-oriented nanofibers with smooth surface and uniform diameters along their lengths. The SBF incubation test confirmed the formation of apatite-like materials, exhibiting enhanced bioactive behavior of the polyurethane/CaCl 2 composite nanofibers. This study demonstrated that the electrospun polyurethane containing CaCl 2 composite nanofibers enhanced the in vitro bioactivity and supports the growth of apatite-like materials.",

author = "R. Nirmala and Nam, \{Ki Taek\} and R. Navamathavan and Park, \{Soo Jin\} and Kim, \{Hak Yong\}",

year = "2012",

month = jan,

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doi = "10.1186/1556-276X-7-2",

language = "English",

volume = "7",

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journal = "Nanoscale Research Letters",

issn = "1931-7573",

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}

TY - JOUR

T1 - Hydroxyapatite mineralization on the calcium chloride blended polyurethane nanofiber via biomimetic method

AU - Nirmala, R.

AU - Nam, Ki Taek

AU - Navamathavan, R.

AU - Park, Soo Jin

AU - Kim, Hak Yong

PY - 2012/1/26

Y1 - 2012/1/26

N2 - Polyurethane nanofibers containing calcium chloride (CaCl 2) were prepared via an electrospinning technique for the biomedical applications. Polyurethane nanofibers with different concentration of CaCl 2 were electrospun, and their bioactivity evaluation was conducted by incubating in biomimetic simulated body fluid (SBF) solution. The morphology, structure and thermal properties of the polyurethane/CaCl 2 composite nanofibers were characterized by means of scanning electron microscopy (SEM), field-emission scanning electron microscopy, energy dispersive X-ray spectroscopy, X-ray diffraction, Fourier transform infrared spectroscopy and thermogravimetry. SEM images revealed that the CaCl 2 salt incorporated homogeneously to form well-oriented nanofibers with smooth surface and uniform diameters along their lengths. The SBF incubation test confirmed the formation of apatite-like materials, exhibiting enhanced bioactive behavior of the polyurethane/CaCl 2 composite nanofibers. This study demonstrated that the electrospun polyurethane containing CaCl 2 composite nanofibers enhanced the in vitro bioactivity and supports the growth of apatite-like materials.

AB - Polyurethane nanofibers containing calcium chloride (CaCl 2) were prepared via an electrospinning technique for the biomedical applications. Polyurethane nanofibers with different concentration of CaCl 2 were electrospun, and their bioactivity evaluation was conducted by incubating in biomimetic simulated body fluid (SBF) solution. The morphology, structure and thermal properties of the polyurethane/CaCl 2 composite nanofibers were characterized by means of scanning electron microscopy (SEM), field-emission scanning electron microscopy, energy dispersive X-ray spectroscopy, X-ray diffraction, Fourier transform infrared spectroscopy and thermogravimetry. SEM images revealed that the CaCl 2 salt incorporated homogeneously to form well-oriented nanofibers with smooth surface and uniform diameters along their lengths. The SBF incubation test confirmed the formation of apatite-like materials, exhibiting enhanced bioactive behavior of the polyurethane/CaCl 2 composite nanofibers. This study demonstrated that the electrospun polyurethane containing CaCl 2 composite nanofibers enhanced the in vitro bioactivity and supports the growth of apatite-like materials.

UR - https://www.scopus.com/pages/publications/84862965771

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DO - 10.1186/1556-276X-7-2

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SN - 1931-7573

VL - 7

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EP - 8

JO - Nanoscale Research Letters

JF - Nanoscale Research Letters

M1 - 2

ER -

Hydroxyapatite mineralization on the calcium chloride blended polyurethane nanofiber via biomimetic method

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