TY - JOUR
T1 - Hydroxyapatite mineralization on the calcium chloride blended polyurethane nanofiber via biomimetic method
AU - Nirmala, R.
AU - Nam, Ki Taek
AU - Navamathavan, R.
AU - Park, Soo Jin
AU - Kim, Hak Yong
PY - 2012/1/26
Y1 - 2012/1/26
N2 - Polyurethane nanofibers containing calcium chloride (CaCl 2) were prepared via an electrospinning technique for the biomedical applications. Polyurethane nanofibers with different concentration of CaCl 2 were electrospun, and their bioactivity evaluation was conducted by incubating in biomimetic simulated body fluid (SBF) solution. The morphology, structure and thermal properties of the polyurethane/CaCl 2 composite nanofibers were characterized by means of scanning electron microscopy (SEM), field-emission scanning electron microscopy, energy dispersive X-ray spectroscopy, X-ray diffraction, Fourier transform infrared spectroscopy and thermogravimetry. SEM images revealed that the CaCl 2 salt incorporated homogeneously to form well-oriented nanofibers with smooth surface and uniform diameters along their lengths. The SBF incubation test confirmed the formation of apatite-like materials, exhibiting enhanced bioactive behavior of the polyurethane/CaCl 2 composite nanofibers. This study demonstrated that the electrospun polyurethane containing CaCl 2 composite nanofibers enhanced the in vitro bioactivity and supports the growth of apatite-like materials.
AB - Polyurethane nanofibers containing calcium chloride (CaCl 2) were prepared via an electrospinning technique for the biomedical applications. Polyurethane nanofibers with different concentration of CaCl 2 were electrospun, and their bioactivity evaluation was conducted by incubating in biomimetic simulated body fluid (SBF) solution. The morphology, structure and thermal properties of the polyurethane/CaCl 2 composite nanofibers were characterized by means of scanning electron microscopy (SEM), field-emission scanning electron microscopy, energy dispersive X-ray spectroscopy, X-ray diffraction, Fourier transform infrared spectroscopy and thermogravimetry. SEM images revealed that the CaCl 2 salt incorporated homogeneously to form well-oriented nanofibers with smooth surface and uniform diameters along their lengths. The SBF incubation test confirmed the formation of apatite-like materials, exhibiting enhanced bioactive behavior of the polyurethane/CaCl 2 composite nanofibers. This study demonstrated that the electrospun polyurethane containing CaCl 2 composite nanofibers enhanced the in vitro bioactivity and supports the growth of apatite-like materials.
UR - https://www.scopus.com/pages/publications/84862965771
U2 - 10.1186/1556-276X-7-2
DO - 10.1186/1556-276X-7-2
M3 - Article
AN - SCOPUS:84862965771
SN - 1931-7573
VL - 7
SP - 1
EP - 8
JO - Nanoscale Research Letters
JF - Nanoscale Research Letters
M1 - 2
ER -