In vitro investigation of electrophoretically deposited bioactive hydroxyapatite/chitosan coatings reinforced by graphene

Marija Đošić, Sanja Eraković, Ana Janković, Maja Vukašinović-Sekulić, Ivana Z. Matić, Jovica Stojanović, Kyong Yop Rhee, Vesna Mišković-Stanković, Soo Jin Park

Research output: Contribution to journalArticlepeer-review

Abstract

Graphene (Gr) and natural polymer chitosan (CS) were introduced to hydroxyapatite (HAP) to produce a three-component composite coating, which was fabricated by cathodic electrophoretic deposition on Ti substrates in an ethanol suspension. These HAP/CS/Gr coatings were characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), thermogravimetric analysis (TGA), X-ray photoelectron spectroscopy (XPS) and electrochemical measurements and found that the graphene into HAP/CS composites significantly improves their morphology, thermal stability, and bioactivity. Both HAP/CS and HAP/CS/Gr composite coatings are classified as non-cytotoxic when tested against healthy peripheral blood mononuclear cells (PBMC), while antibacterial activity against Staphylococcus aureus and Escherichia coli could not be verified.

Original languageEnglish
Pages (from-to)336-347
Number of pages12
JournalJournal of Industrial and Engineering Chemistry
Volume47
DOIs
Publication statusPublished - 25 Mar 2017
Externally publishedYes

Keywords

  • Coating materials
  • Composite materials
  • Electrochemical impedance spectroscopy
  • Scanning electron microscopy
  • X-ray diffraction

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