Long-lived fluorescence of homopolymeric guanine-cytosine DNA duplexes

Ignacio Vayá; Pascale Changenet-Barret; Thomas Gustavsson; Dragoslav Zikich; Alexander B. Kotlyar; Dimitra Markovitsi

doi:10.1039/c0pp00201a

Long-lived fluorescence of homopolymeric guanine-cytosine DNA duplexes

Ignacio Vayá
, Pascale Changenet-Barret
, Thomas Gustavsson
, Dragoslav Zikich
, Alexander B. Kotlyar
, Dimitra Markovitsi

Research output: Contribution to journal › Article › peer-review

Abstract

The fluorescence spectrum of the homopolymeric double helix poly(dG)·poly(dC) is dominated by emission decaying on the nanosecond time-scale, as previously reported for the alternating homologue poly(dGdC)·poly(dGdC). Thus, energy trapping over long periods of time is a common feature of GC duplexes which contrast with AT duplexes. The impact of such behaviour on DNA photodamage needs to be evaluated.

Original language	English
Pages (from-to)	1193-1195
Number of pages	3
Journal	Photochemical and Photobiological Sciences
Volume	9
Issue number	9
DOIs	https://doi.org/10.1039/c0pp00201a
Publication status	Published - 1 Jan 2010
Externally published	Yes

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10.1039/c0pp00201a

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title = "Long-lived fluorescence of homopolymeric guanine-cytosine DNA duplexes",

abstract = "The fluorescence spectrum of the homopolymeric double helix poly(dG)·poly(dC) is dominated by emission decaying on the nanosecond time-scale, as previously reported for the alternating homologue poly(dGdC)·poly(dGdC). Thus, energy trapping over long periods of time is a common feature of GC duplexes which contrast with AT duplexes. The impact of such behaviour on DNA photodamage needs to be evaluated.",

author = "Ignacio Vay{\'a} and Pascale Changenet-Barret and Thomas Gustavsson and Dragoslav Zikich and Kotlyar, \{Alexander B.\} and Dimitra Markovitsi",

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T1 - Long-lived fluorescence of homopolymeric guanine-cytosine DNA duplexes

AU - Vayá, Ignacio

AU - Changenet-Barret, Pascale

AU - Gustavsson, Thomas

AU - Zikich, Dragoslav

AU - Kotlyar, Alexander B.

AU - Markovitsi, Dimitra

PY - 2010/1/1

Y1 - 2010/1/1

N2 - The fluorescence spectrum of the homopolymeric double helix poly(dG)·poly(dC) is dominated by emission decaying on the nanosecond time-scale, as previously reported for the alternating homologue poly(dGdC)·poly(dGdC). Thus, energy trapping over long periods of time is a common feature of GC duplexes which contrast with AT duplexes. The impact of such behaviour on DNA photodamage needs to be evaluated.

AB - The fluorescence spectrum of the homopolymeric double helix poly(dG)·poly(dC) is dominated by emission decaying on the nanosecond time-scale, as previously reported for the alternating homologue poly(dGdC)·poly(dGdC). Thus, energy trapping over long periods of time is a common feature of GC duplexes which contrast with AT duplexes. The impact of such behaviour on DNA photodamage needs to be evaluated.

U2 - 10.1039/c0pp00201a

DO - 10.1039/c0pp00201a

M3 - Article

AN - SCOPUS:77956046099

SN - 1474-905X

VL - 9

SP - 1193

EP - 1195

JO - Photochemical and Photobiological Sciences

JF - Photochemical and Photobiological Sciences

IS - 9

ER -

Long-lived fluorescence of homopolymeric guanine-cytosine DNA duplexes

Abstract

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