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Luminescent lanthanide-ion doped nanoparticles as singlebiomolecule labels and oxidant sensors

  • Institut Polytechnique de Paris

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

We report on the single-particle properties of lanthanide-ion doped oxide nanoparticles. We have demonstrated that their size can be accurately determined from their luminosity. The optically determined size distribution is in very good agreement with the distribution obtained from transmission electron microscopy (TEM). We also showed that the photobleaching of these nanoparticles is related to a reduction process and that we can use it to sense in a concentration-dependent manner the presence of an oxidant like H 2O2. Finally, we propose a way to perform nanoparticle-protein coupling and to determine the protein-nanoparticle ratio at the single-particle level.

Original languageEnglish
Title of host publicationColloidal Quantum Dots for Biomedical Applications II
DOIs
Publication statusPublished - 3 Sept 2007
EventColloidal Quantum Dots for Biomedical Applications II - San Jose, CA, United States
Duration: 20 Jan 200723 Jan 2007

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume6448
ISSN (Print)1605-7422

Conference

ConferenceColloidal Quantum Dots for Biomedical Applications II
Country/TerritoryUnited States
CitySan Jose, CA
Period20/01/0723/01/07

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