Mapping metabolism and myelin dynamics in live brain tissue by label-free multimodal non-linear microscopy

Bahar Asadipour; Josephine Morizet; Remi Ronzano; Xingjian Zhang; Anatole Chessel; Pierre Mahou; Xavier Solinas; Marie Stéphane Aigrot; Anne Desmazieres; Bruno Stankoff; Emmanuel Beaurepaire; Chiara Stringari

doi:10.1364/NTM.2025.NTh3B.2

Mapping metabolism and myelin dynamics in live brain tissue by label-free multimodal non-linear microscopy

Bahar Asadipour
, Josephine Morizet
, Remi Ronzano
, Xingjian Zhang
, Anatole Chessel
, Pierre Mahou
, Xavier Solinas
, Marie Stéphane Aigrot
, Anne Desmazieres
, Bruno Stankoff
, Emmanuel Beaurepaire
, Chiara Stringari

Institut Polytechnique de Paris
Institut du Cerveau et de la Moelle épinière (ICM)

Research output: Contribution to conference › Paper › peer-review

Abstract

Here we develop label-free optical methods to probe metabolism at the cellular level and visualize myelin at the single fiber level to investigate how neuron-glia metabolic coupling shapes myelin plasticity in the brain.

Original language	English
DOIs	https://doi.org/10.1364/NTM.2025.NTh3B.2
Publication status	Published - 1 Jan 2025
Event	2025 Novel Techniques in Microscopy, NTM 2025 - Coronado, United States Duration: 21 Apr 2025 → 24 Apr 2025

Conference

Conference	2025 Novel Techniques in Microscopy, NTM 2025
Country/Territory	United States
City	Coronado
Period	21/04/25 → 24/04/25

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10.1364/NTM.2025.NTh3B.2

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Asadipour, B., Morizet, J., Ronzano, R., Zhang, X., Chessel, A., Mahou, P., Solinas, X., Aigrot, M. S., Desmazieres, A., Stankoff, B., Beaurepaire, E., & Stringari, C. (2025). Mapping metabolism and myelin dynamics in live brain tissue by label-free multimodal non-linear microscopy. Paper presented at 2025 Novel Techniques in Microscopy, NTM 2025, Coronado, United States. https://doi.org/10.1364/NTM.2025.NTh3B.2

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title = "Mapping metabolism and myelin dynamics in live brain tissue by label-free multimodal non-linear microscopy",

abstract = "Here we develop label-free optical methods to probe metabolism at the cellular level and visualize myelin at the single fiber level to investigate how neuron-glia metabolic coupling shapes myelin plasticity in the brain.",

author = "Bahar Asadipour and Josephine Morizet and Remi Ronzano and Xingjian Zhang and Anatole Chessel and Pierre Mahou and Xavier Solinas and Aigrot, \{Marie St{\'e}phane\} and Anne Desmazieres and Bruno Stankoff and Emmanuel Beaurepaire and Chiara Stringari",

note = "Publisher Copyright: This Article {\textcopyright} 2025 The Author(s); 2025 Novel Techniques in Microscopy, NTM 2025 ; Conference date: 21-04-2025 Through 24-04-2025",

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doi = "10.1364/NTM.2025.NTh3B.2",

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Asadipour, B, Morizet, J, Ronzano, R, Zhang, X, Chessel, A , Mahou, P, Solinas, X, Aigrot, MS, Desmazieres, A, Stankoff, B, Beaurepaire, E & Stringari, C 2025, 'Mapping metabolism and myelin dynamics in live brain tissue by label-free multimodal non-linear microscopy', Paper presented at 2025 Novel Techniques in Microscopy, NTM 2025, Coronado, United States, 21/04/25 - 24/04/25. https://doi.org/10.1364/NTM.2025.NTh3B.2

TY - CONF

T1 - Mapping metabolism and myelin dynamics in live brain tissue by label-free multimodal non-linear microscopy

AU - Asadipour, Bahar

AU - Morizet, Josephine

AU - Ronzano, Remi

AU - Zhang, Xingjian

AU - Chessel, Anatole

AU - Mahou, Pierre

AU - Solinas, Xavier

AU - Aigrot, Marie Stéphane

AU - Desmazieres, Anne

AU - Stankoff, Bruno

AU - Beaurepaire, Emmanuel

AU - Stringari, Chiara

PY - 2025/1/1

Y1 - 2025/1/1

N2 - Here we develop label-free optical methods to probe metabolism at the cellular level and visualize myelin at the single fiber level to investigate how neuron-glia metabolic coupling shapes myelin plasticity in the brain.

AB - Here we develop label-free optical methods to probe metabolism at the cellular level and visualize myelin at the single fiber level to investigate how neuron-glia metabolic coupling shapes myelin plasticity in the brain.

UR - https://www.scopus.com/pages/publications/105010830589

U2 - 10.1364/NTM.2025.NTh3B.2

DO - 10.1364/NTM.2025.NTh3B.2

M3 - Paper

AN - SCOPUS:105010830589

T2 - 2025 Novel Techniques in Microscopy, NTM 2025

Y2 - 21 April 2025 through 24 April 2025

ER -

Mapping metabolism and myelin dynamics in live brain tissue by label-free multimodal non-linear microscopy

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