Abstract
Quantitative systems pharmacology (QSP) models are progressively entering the arena of contemporary pharmacology. The efficient implementation and evaluation of complex QSP models necessitates the development of flexible computational tools that are built into QSP mainstream software. To this end, we present MatVPC, a versatile MATLAB-based tool that accommodates QSP models of any complexity level. MatVPC executes Monte Carlo simulations as well as automatic construction of visual predictive checks (VPCs) and quantified VPCs (QVPCs).
| Original language | English |
|---|---|
| Pages (from-to) | 547-557 |
| Number of pages | 11 |
| Journal | CPT: Pharmacometrics and Systems Pharmacology |
| Volume | 4 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - 1 Sept 2015 |
| Externally published | Yes |