Mean first-passage time to a small absorbing target in an elongated planar domain

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Abstract

We derive an approximate but fully explicit formula for the mean first-passage time (MFPT) to a small absorbing target of arbitrary shape in a general elongated domain in the plane. Our approximation combines conformal mapping, boundary homogenisation, and Fick-Jacobs equation to express the MFPT in terms of diffusivity and geometric parameters. A systematic comparison with a numerical solution of the original problem validates its accuracy when the starting point is not too close to the target. This is a practical tool for a rapid estimation of the MFPT for various applications in chemical physics and biology.

Original languageEnglish
Article number113024
JournalNew Journal of Physics
Volume22
Issue number11
DOIs
Publication statusPublished - 1 Nov 2020

Keywords

  • diffusion
  • elongated domain
  • first-passage time
  • homogenisation
  • reactivity

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