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Multiscale conformational dynamics probed by time-resolved circular dichroism

  • Institut Polytechnique de Paris

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Measuring circular dichroism in time-resolved experiments is very promising to investigate the dynamics of conformational changes occurring in chemical or biological processes. This is however very challenging because of the weakness of the signals. Here we present several complementary set-ups which allow us to investigate changes in CD on a large range of timescales, from picoseconds to milliseconds. These set-ups are utilized to probe (i) the dynamics of the dihedral angle in Binaphthol following photoexcitation, (ii) the first step in the photoisomerization process in Photoactive Yellow Protein, and (iii) folding/unfolding processes of DNA G-quadruplexes.

Original languageEnglish
Title of host publicationOrganic Photonic Materials and Devices XX
EditorsChristopher E. Tabor, Francois Kajzar, Toshikuni Kaino, Yasuhiro Koike
PublisherSPIE
ISBN (Electronic)9781510615434
DOIs
Publication statusPublished - 1 Jan 2018
EventOrganic Photonic Materials and Devices XX 2018 - San Francisco, United States
Duration: 31 Jan 20181 Feb 2018

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume10529
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Conference

ConferenceOrganic Photonic Materials and Devices XX 2018
Country/TerritoryUnited States
CitySan Francisco
Period31/01/181/02/18

Keywords

  • conformational changes
  • time-resolved circular dichroism

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