Nef-Perkow cascade towards imidazo phosphate derivatives

Somayeh Ghorbani; Ebrahim Soleimani; Laurent El Kaïm

doi:10.1016/j.tetlet.2017.10.055

Nef-Perkow cascade towards imidazo phosphate derivatives

Somayeh Ghorbani
, Ebrahim Soleimani
, Laurent El Kaïm

Research output: Contribution to journal › Article › peer-review

Abstract

A one-pot four-component synthesis of imidazo phosphates has been achieved using a Nef/Perkow sequence followed by addition of propargylamine to form an intermediate amidrazone. The latter is not isolated but directly cyclized to imidazo phosphate derivatives in the presence of silver carbonate.

Original language	English
Pages (from-to)	4595-4597
Number of pages	3
Journal	Tetrahedron Letters
Volume	58
Issue number	49
DOIs	https://doi.org/10.1016/j.tetlet.2017.10.055
Publication status	Published - 6 Dec 2017
Externally published	Yes

Keywords

Hydroamination
Isocyanide
Nef
Perkow
Vinyl phosphate

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10.1016/j.tetlet.2017.10.055

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@article{326fcfca5358476eab13f31f7524d6bf,

title = "Nef-Perkow cascade towards imidazo phosphate derivatives",

abstract = "A one-pot four-component synthesis of imidazo phosphates has been achieved using a Nef/Perkow sequence followed by addition of propargylamine to form an intermediate amidrazone. The latter is not isolated but directly cyclized to imidazo phosphate derivatives in the presence of silver carbonate.",

keywords = "Hydroamination, Isocyanide, Nef, Perkow, Vinyl phosphate",

author = "Somayeh Ghorbani and Ebrahim Soleimani and \{El Ka{\"i}m\}, Laurent",

note = "Publisher Copyright: {\textcopyright} 2017 Elsevier Ltd",

year = "2017",

month = dec,

day = "6",

doi = "10.1016/j.tetlet.2017.10.055",

language = "English",

volume = "58",

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journal = "Tetrahedron Letters",

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TY - JOUR

T1 - Nef-Perkow cascade towards imidazo phosphate derivatives

AU - Ghorbani, Somayeh

AU - Soleimani, Ebrahim

AU - El Kaïm, Laurent

PY - 2017/12/6

Y1 - 2017/12/6

N2 - A one-pot four-component synthesis of imidazo phosphates has been achieved using a Nef/Perkow sequence followed by addition of propargylamine to form an intermediate amidrazone. The latter is not isolated but directly cyclized to imidazo phosphate derivatives in the presence of silver carbonate.

AB - A one-pot four-component synthesis of imidazo phosphates has been achieved using a Nef/Perkow sequence followed by addition of propargylamine to form an intermediate amidrazone. The latter is not isolated but directly cyclized to imidazo phosphate derivatives in the presence of silver carbonate.

KW - Hydroamination

KW - Isocyanide

KW - Nef

KW - Perkow

KW - Vinyl phosphate

U2 - 10.1016/j.tetlet.2017.10.055

DO - 10.1016/j.tetlet.2017.10.055

M3 - Article

AN - SCOPUS:85033360088

SN - 0040-4039

VL - 58

SP - 4595

EP - 4597

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 49

ER -

Nef-Perkow cascade towards imidazo phosphate derivatives

Abstract

Keywords

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