New Ugi-Smiles-metathesis strategy toward the synthesis of pyrimido azepines

Laurent El Kaïm; Laurence Grimaud; Julie Oble

doi:10.1021/jo070706c

New Ugi-Smiles-metathesis strategy toward the synthesis of pyrimido azepines

Laurent El Kaïm
, Laurence Grimaud
, Julie Oble

Unité Chimie et Procédés

Research output: Contribution to journal › Article › peer-review

Abstract

(Chemical Equation Presented) A new strategy involving Ugi-Smiles coupling followed by ring-closure metathesis is described herein for the preparation of pyrimidine-fused heterocyclic scaffolds. The scope of this sequence is presented in relation with the heteroatom effect observed in the Ugi-Smiles coupling.

Original language	English
Pages (from-to)	5835-5838
Number of pages	4
Journal	Journal of Organic Chemistry
Volume	72
Issue number	15
DOIs	https://doi.org/10.1021/jo070706c
Publication status	Published - 20 Jul 2007
Externally published	Yes

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title = "New Ugi-Smiles-metathesis strategy toward the synthesis of pyrimido azepines",

abstract = "(Chemical Equation Presented) A new strategy involving Ugi-Smiles coupling followed by ring-closure metathesis is described herein for the preparation of pyrimidine-fused heterocyclic scaffolds. The scope of this sequence is presented in relation with the heteroatom effect observed in the Ugi-Smiles coupling.",

author = "\{El Ka{\"i}m\}, Laurent and Laurence Grimaud and Julie Oble",

year = "2007",

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AU - El Kaïm, Laurent

AU - Grimaud, Laurence

AU - Oble, Julie

PY - 2007/7/20

Y1 - 2007/7/20

N2 - (Chemical Equation Presented) A new strategy involving Ugi-Smiles coupling followed by ring-closure metathesis is described herein for the preparation of pyrimidine-fused heterocyclic scaffolds. The scope of this sequence is presented in relation with the heteroatom effect observed in the Ugi-Smiles coupling.

AB - (Chemical Equation Presented) A new strategy involving Ugi-Smiles coupling followed by ring-closure metathesis is described herein for the preparation of pyrimidine-fused heterocyclic scaffolds. The scope of this sequence is presented in relation with the heteroatom effect observed in the Ugi-Smiles coupling.

U2 - 10.1021/jo070706c

DO - 10.1021/jo070706c

M3 - Article

AN - SCOPUS:34547124310

SN - 0022-3263

VL - 72

SP - 5835

EP - 5838

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 15

ER -

New Ugi-Smiles-metathesis strategy toward the synthesis of pyrimido azepines

Abstract

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