Nitrile synthesis through catalyzed cascades involving acid-nitrile exchange

Damien Cartigny; Aurélie Dos Santos; Laurent El Kaïm; Laurence Grimaud; Roland Jacquot; Philippe Marion

doi:10.1055/s-0033-1341227

Nitrile synthesis through catalyzed cascades involving acid-nitrile exchange

Damien Cartigny, Aurélie Dos Santos, Laurent El Kaïm, Laurence Grimaud, Roland Jacquot, Philippe Marion

Research output: Contribution to journal › Article › peer-review

Abstract

Irreversible acid-nitrile exchange reactions using both glutaronitrile and (phenylsulfonyl)acetonitrile may be catalyzed by Lewis acids. Whereas a cyclization towards imides displaces the equilibria in the reaction with dinitriles, a decarboxylation step is involved when using the (phenylsulfonyl)acetonitrile.

Original language	English
Article number	SS-2014-T0131-OP
Pages (from-to)	1802-1806
Number of pages	5
Journal	Synthesis
Volume	46
Issue number	13
DOIs	https://doi.org/10.1055/s-0033-1341227
Publication status	Published - 1 Jan 2014
Externally published	Yes

Keywords

Lewis acids
acylation
carboxylic acids
imides
nitriles

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10.1055/s-0033-1341227

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title = "Nitrile synthesis through catalyzed cascades involving acid-nitrile exchange",

abstract = "Irreversible acid-nitrile exchange reactions using both glutaronitrile and (phenylsulfonyl)acetonitrile may be catalyzed by Lewis acids. Whereas a cyclization towards imides displaces the equilibria in the reaction with dinitriles, a decarboxylation step is involved when using the (phenylsulfonyl)acetonitrile.",

keywords = "Lewis acids, acylation, carboxylic acids, imides, nitriles",

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AU - Cartigny, Damien

AU - Dos Santos, Aurélie

AU - El Kaïm, Laurent

AU - Grimaud, Laurence

AU - Jacquot, Roland

AU - Marion, Philippe

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Irreversible acid-nitrile exchange reactions using both glutaronitrile and (phenylsulfonyl)acetonitrile may be catalyzed by Lewis acids. Whereas a cyclization towards imides displaces the equilibria in the reaction with dinitriles, a decarboxylation step is involved when using the (phenylsulfonyl)acetonitrile.

AB - Irreversible acid-nitrile exchange reactions using both glutaronitrile and (phenylsulfonyl)acetonitrile may be catalyzed by Lewis acids. Whereas a cyclization towards imides displaces the equilibria in the reaction with dinitriles, a decarboxylation step is involved when using the (phenylsulfonyl)acetonitrile.

KW - Lewis acids

KW - acylation

KW - carboxylic acids

KW - imides

KW - nitriles

U2 - 10.1055/s-0033-1341227

DO - 10.1055/s-0033-1341227

M3 - Article

AN - SCOPUS:84903280050

SN - 0039-7881

VL - 46

SP - 1802

EP - 1806

JO - Synthesis

JF - Synthesis

IS - 13

M1 - SS-2014-T0131-OP

ER -

Nitrile synthesis through catalyzed cascades involving acid-nitrile exchange

Abstract

Keywords

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