One-pot synthesis of 3-alkylidenephthalides from benzoic acids by a rhodium-catalyzed ortho-C - H acylation process

Grégory Danoun; Patrizia Mamone; Lukas J. Gooßen

doi:10.1002/chem.201303426

One-pot synthesis of 3-alkylidenephthalides from benzoic acids by a rhodium-catalyzed ortho-C - H acylation process

Grégory Danoun, Patrizia Mamone, Lukas J. Gooßen

University of Kaiserslautern

Research output: Contribution to journal › Article › peer-review

Abstract

C - H functionalization: A [Rh(cod)Cl]₂/CsF (cod=1,5- cyclooctadiene) catalyst system was found to promote the straightforward synthesis of 3-alkylidenephthalides from benzoic acids and aliphatic acids or anhydrides through a one-pot C - H acylation/acylalization/elimination cascade (see scheme).

Original language	English
Pages (from-to)	17287-17290
Number of pages	4
Journal	Chemistry - A European Journal
Volume	19
Issue number	51
DOIs	https://doi.org/10.1002/chem.201303426
Publication status	Published - 16 Dec 2013
Externally published	Yes

Keywords

C - H functionalization
alkylidenephthalides
anhydrides
benzoic acids
rhodium

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10.1002/chem.201303426

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title = "One-pot synthesis of 3-alkylidenephthalides from benzoic acids by a rhodium-catalyzed ortho-C - H acylation process",

abstract = "C - H functionalization: A [Rh(cod)Cl]2/CsF (cod=1,5- cyclooctadiene) catalyst system was found to promote the straightforward synthesis of 3-alkylidenephthalides from benzoic acids and aliphatic acids or anhydrides through a one-pot C - H acylation/acylalization/elimination cascade (see scheme).",

keywords = "C - H functionalization, alkylidenephthalides, anhydrides, benzoic acids, rhodium",

author = "Gr{\'e}gory Danoun and Patrizia Mamone and Goo{\ss}en, \{Lukas J.\}",

year = "2013",

month = dec,

day = "16",

doi = "10.1002/chem.201303426",

language = "English",

volume = "19",

pages = "17287--17290",

journal = "Chemistry - A European Journal",

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AU - Danoun, Grégory

AU - Mamone, Patrizia

AU - Gooßen, Lukas J.

PY - 2013/12/16

Y1 - 2013/12/16

N2 - C - H functionalization: A [Rh(cod)Cl]2/CsF (cod=1,5- cyclooctadiene) catalyst system was found to promote the straightforward synthesis of 3-alkylidenephthalides from benzoic acids and aliphatic acids or anhydrides through a one-pot C - H acylation/acylalization/elimination cascade (see scheme).

AB - C - H functionalization: A [Rh(cod)Cl]2/CsF (cod=1,5- cyclooctadiene) catalyst system was found to promote the straightforward synthesis of 3-alkylidenephthalides from benzoic acids and aliphatic acids or anhydrides through a one-pot C - H acylation/acylalization/elimination cascade (see scheme).

KW - C - H functionalization

KW - alkylidenephthalides

KW - anhydrides

KW - benzoic acids

KW - rhodium

U2 - 10.1002/chem.201303426

DO - 10.1002/chem.201303426

M3 - Article

C2 - 24227020

AN - SCOPUS:84890117885

SN - 0947-6539

VL - 19

SP - 17287

EP - 17290

JO - Chemistry - A European Journal

JF - Chemistry - A European Journal

IS - 51

ER -

One-pot synthesis of 3-alkylidenephthalides from benzoic acids by a rhodium-catalyzed ortho-C - H acylation process

Abstract

Keywords

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