Oxime derivatives as α-electrophiles. from α-tetralone oximes to tetracyclic frameworks

Béatrice Quiclet-Sire; Nina Tölle; Syeda Nahid Zafar; Samir Z. Zard

doi:10.1021/ol2012204

Oxime derivatives as α-electrophiles. from α-tetralone oximes to tetracyclic frameworks

Béatrice Quiclet-Sire
, Nina Tölle
, Syeda Nahid Zafar
, Samir Z. Zard

Laboratoire de Synthèse Organique

Research output: Contribution to journal › Article › peer-review

Abstract

When subjected to the conditions of a Semmler-Wolff/Schroeter aromatization, the oximes of 4-benzyl-substituted tetralones undergo an electrophilic aromatic substitution reaction to form tetracyclic frameworks.

Original language	English
Pages (from-to)	3266-3269
Number of pages	4
Journal	Organic Letters
Volume	13
Issue number	12
DOIs	https://doi.org/10.1021/ol2012204
Publication status	Published - 17 Jun 2011
Externally published	Yes

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@article{78bba0b34e6446d8b487d3d58c3f677e,

title = "Oxime derivatives as α-electrophiles. from α-tetralone oximes to tetracyclic frameworks",

abstract = "When subjected to the conditions of a Semmler-Wolff/Schroeter aromatization, the oximes of 4-benzyl-substituted tetralones undergo an electrophilic aromatic substitution reaction to form tetracyclic frameworks.",

author = "B{\'e}atrice Quiclet-Sire and Nina T{\"o}lle and Zafar, \{Syeda Nahid\} and Zard, \{Samir Z.\}",

year = "2011",

month = jun,

day = "17",

doi = "10.1021/ol2012204",

language = "English",

volume = "13",

pages = "3266--3269",

journal = "Organic Letters",

issn = "1523-7060",

number = "12",

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T1 - Oxime derivatives as α-electrophiles. from α-tetralone oximes to tetracyclic frameworks

AU - Quiclet-Sire, Béatrice

AU - Tölle, Nina

AU - Zafar, Syeda Nahid

AU - Zard, Samir Z.

PY - 2011/6/17

Y1 - 2011/6/17

N2 - When subjected to the conditions of a Semmler-Wolff/Schroeter aromatization, the oximes of 4-benzyl-substituted tetralones undergo an electrophilic aromatic substitution reaction to form tetracyclic frameworks.

AB - When subjected to the conditions of a Semmler-Wolff/Schroeter aromatization, the oximes of 4-benzyl-substituted tetralones undergo an electrophilic aromatic substitution reaction to form tetracyclic frameworks.

U2 - 10.1021/ol2012204

DO - 10.1021/ol2012204

M3 - Article

AN - SCOPUS:79958842993

SN - 1523-7060

VL - 13

SP - 3266

EP - 3269

JO - Organic Letters

JF - Organic Letters

IS - 12

ER -

Oxime derivatives as α-electrophiles. from α-tetralone oximes to tetracyclic frameworks

Abstract

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