Palladium-Mediated Labeling of Nucleic Acids

Eric Defrancq; Samir Messaoudi

doi:10.1002/cbic.201600599

Palladium-Mediated Labeling of Nucleic Acids

Eric Defrancq
, Samir Messaoudi

Research output: Contribution to journal › Review article › peer-review

Abstract

New applications of Pd-catalyzed coupling reactions (Suzuki–Miyaura, Sonogashira, and Stille–Migita coupling) for post-conjugation of nucleic acids have been developed recently. Breakthroughs in this area might now pave the way for the development of sophisticated DNA probes, which might be of great interest in chemical biology, nanotechnology, and bioanalysis, as well as in diagnostic domains.

Original language	English
Pages (from-to)	426-431
Number of pages	6
Journal	ChemBioChem
Volume	18
Issue number	5
DOIs	https://doi.org/10.1002/cbic.201600599
Publication status	Published - 2 Mar 2017
Externally published	Yes

Keywords

Suzuki–Miyaura
cross-coupling
nucleic acids
oligonucleotides
palladium

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10.1002/cbic.201600599

Cite this

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abstract = "New applications of Pd-catalyzed coupling reactions (Suzuki–Miyaura, Sonogashira, and Stille–Migita coupling) for post-conjugation of nucleic acids have been developed recently. Breakthroughs in this area might now pave the way for the development of sophisticated DNA probes, which might be of great interest in chemical biology, nanotechnology, and bioanalysis, as well as in diagnostic domains.",

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author = "Eric Defrancq and Samir Messaoudi",

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AU - Messaoudi, Samir

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N2 - New applications of Pd-catalyzed coupling reactions (Suzuki–Miyaura, Sonogashira, and Stille–Migita coupling) for post-conjugation of nucleic acids have been developed recently. Breakthroughs in this area might now pave the way for the development of sophisticated DNA probes, which might be of great interest in chemical biology, nanotechnology, and bioanalysis, as well as in diagnostic domains.

AB - New applications of Pd-catalyzed coupling reactions (Suzuki–Miyaura, Sonogashira, and Stille–Migita coupling) for post-conjugation of nucleic acids have been developed recently. Breakthroughs in this area might now pave the way for the development of sophisticated DNA probes, which might be of great interest in chemical biology, nanotechnology, and bioanalysis, as well as in diagnostic domains.

KW - Suzuki–Miyaura

KW - cross-coupling

KW - nucleic acids

KW - oligonucleotides

KW - palladium

UR - https://www.scopus.com/pages/publications/85013046141

U2 - 10.1002/cbic.201600599

DO - 10.1002/cbic.201600599

M3 - Review article

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AN - SCOPUS:85013046141

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VL - 18

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JO - ChemBioChem

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ER -

Palladium-Mediated Labeling of Nucleic Acids

Abstract

Keywords

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