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Passerini/Friedel-crafts route towards indole derivatives

Research output: Contribution to journalArticlepeer-review

Abstract

The Passerini adducts of various electron-rich aromatic aldehydes with pivalic acid were used as electrophiles towards indoles in a Friedel-Crafts-type reaction. The Friedel-Crafts step was performed under microwave conditions using a catalytic amount of FeCl3.

Original languageEnglish
Article numberst-2016-b0247-l
Pages (from-to)2571-2574
Number of pages4
JournalSynlett
Volume27
Issue number18
DOIs
Publication statusPublished - 14 Nov 2016

Keywords

  • Friedel-Crafts
  • Passerini
  • indoles
  • iron chloride catalyst

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