Picosecond time-resolved resonance Raman investigation of primary structural transition of the heme induced by nitric oxide rebinding

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Abstract

We probed the heme iron motion for several proteins by measuring the evolution of the iron-histidine Raman band intensity during nitric oxide (NO) rebinding. Whereas NO dissociation induces quasi-instantaneous iron motion and heme doming, the reverse primary movement of the iron towards the planar heme after NO binding is delayed and varies among proteins (7-30 ps).

Original languageEnglish
Title of host publicationInternational Conference on Ultrafast Phenomena, UP 2010
PublisherOptical Society of America (OSA)
ISBN (Print)9781557528940
DOIs
Publication statusPublished - 1 Jan 2010
EventInternational Conference on Ultrafast Phenomena, UP 2010 - Snowmass Village, CO, United States
Duration: 18 Jul 201023 Jul 2010

Publication series

NameOptics InfoBase Conference Papers
ISSN (Electronic)2162-2701

Conference

ConferenceInternational Conference on Ultrafast Phenomena, UP 2010
Country/TerritoryUnited States
CitySnowmass Village, CO
Period18/07/1023/07/10

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